NCKX1 Antibody (E-6): sc-393400
- NCKX1 Antibody (E-6) is a mouse monoclonal IgG1 κ NCKX1 antibody, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 94-380 mapping near the N-terminus of NCKX1 of human origin
- NCKX1 Antibody (E-6) is recommended for detection of NCKX1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-NCKX1 Antibody (E-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for NCKX1 Antibody (E-6) for WB applications. These reagents are now offered in bundles with NCKX1 Antibody (E-6) (see ordering information below).
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NCKX1 Antibody (E-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects NCKX1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NCKX1 (E-6) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. NCKX1 protein, also known as solute carrier family 24, member 1 (SLC24A1) or sodium/calcium/potassium exchanger 1, plays a crucial role in maintaining cellular ion homeostasis by facilitating the exchange of sodium, calcium, and potassium ions across the plasma membrane. This function is vital for processes such as neuronal signaling and muscle contraction, as NCKX1 helps regulate intracellular calcium levels, which are essential for various cellular activities. NCKX1 protein is primarily located in the plasma membrane of excitable cells, including neurons and muscle cells, where NCKX1 activity is critical for preventing calcium overload and ensuring proper cellular function. Anti-NCKX1 antibody (E-6) provides a reliable tool for researchers studying the physiological and pathological roles of this important protein in various biological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
NCKX1 Antibody (E-6) References:
- cDNA cloning and functional expression of the dolphin retinal rod Na-Ca+K exchanger NCKX1: comparison with the functionally silent bovine NCKX1. | Cooper, CB., et al. 1999. Biochemistry. 38: 6276-83. PMID: 10320357
- Alternatively spliced isoforms of the rat eye sodium/calcium+potassium exchanger NCKX1. | Poon, S., et al. 2000. Am J Physiol Cell Physiol. 278: C651-60. PMID: 10751314
- Signal sequence cleavage and plasma membrane targeting of the retinal rod NCKX1 and cone NCKX2 Na+/Ca2+ - K+ exchangers. | Kang, K. and Schnetkamp, PP. 2003. Biochemistry. 42: 9438-45. PMID: 12899631
- Substitution of a single residue, Asp575, renders the NCKX2 K+-dependent Na+/Ca2+ exchanger independent of K+. | Kang, KJ., et al. 2005. J Biol Chem. 280: 6834-9. PMID: 15611132
- Modulation of Ca2+ signaling by Na+/Ca2+ exchangers in mast cells. | Aneiros, E., et al. 2005. J Immunol. 174: 119-30. PMID: 15611234
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NCKX1 Antibody (E-6) | sc-393400 | 200 µg/ml | $322.00 | |||
NCKX1 Antibody (E-6): m-IgG Fc BP-HRP Bundle | sc-530444 | 200 µg Ab; 10 µg BP | $361.00 | |||
NCKX1 Antibody (E-6): m-IgGκ BP-HRP Bundle | sc-523929 | 200 µg Ab, 40 µg BP | $361.00 | |||
NCKX1 Antibody (E-6): m-IgG1 BP-HRP Bundle | sc-544055 | 200 µg Ab; 20 µg BP | $361.00 | |||
NCKX1 Antibody (E-6) AC | sc-393400 AC | 500 µg/ml, 25% agarose | $424.00 | |||
NCKX1 Antibody (E-6) HRP | sc-393400 HRP | 200 µg/ml | $322.00 | |||
NCKX1 Antibody (E-6) FITC | sc-393400 FITC | 200 µg/ml | $336.00 | |||
NCKX1 Antibody (E-6) PE | sc-393400 PE | 200 µg/ml | $349.00 | |||
NCKX1 Antibody (E-6) Alexa Fluor® 488 | sc-393400 AF488 | 200 µg/ml | $364.00 | |||
NCKX1 Antibody (E-6) Alexa Fluor® 546 | sc-393400 AF546 | 200 µg/ml | $364.00 | |||
NCKX1 Antibody (E-6) Alexa Fluor® 594 | sc-393400 AF594 | 200 µg/ml | $364.00 | |||
NCKX1 Antibody (E-6) Alexa Fluor® 647 | sc-393400 AF647 | 200 µg/ml | $364.00 | |||
NCKX1 Antibody (E-6) Alexa Fluor® 680 | sc-393400 AF680 | 200 µg/ml | $364.00 | |||
NCKX1 Antibody (E-6) Alexa Fluor® 790 | sc-393400 AF790 | 200 µg/ml | $364.00 |