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NCAM/CD56 Antibody (2Q692): sc-71647

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Datasheets
  • NCAM/CD56 Antibody (2Q692) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • raised against CD56 positive cells of human origin
  • recommended for detection of NCAM of human origin by WB, IP, IF, IHC(P) and FCM; non cross-reactive with NCAM of mouse origin
  • See NCAM/CD56 (123C3): sc-7326 for NCAM/CD56 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for NCAM/CD56 Antibody (2Q692) for WB and IHC(P) applications. These reagents are now offered in bundles with NCAM/CD56 Antibody (2Q692) (see ordering information below).

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    NCAM Antibody (2Q692) is a mouse monoclonal IgG1 kappa light chain antibody specifically engineered to recognize the human Neural Cell Adhesion Molecule (NCAM), also known as CD56 or NCAM1. NCAM is a vital cell surface glycoprotein located on the plasma membrane, where it facilitates crucial cell-to-cell interactions essential for neural development, synaptic plasticity, and the maintenance of neural networks. This strategic localization on the cell surface enables NCAM to mediate interactions between neurons, playing a pivotal role in embryogenesis and the formation of the nervous system. anti-NCAM antibody (C5.9) detects human NCAM through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM), though does not cross-react with mouse NCAM. NCAM (C5.9) antibody makes an invaluable tool for studying NCAM′s involvement in both normal physiological functions and pathological conditions. NCAM expression is prominently observed in several human tumors, including neuroblastomas, rhabdomyosarcomas, Wilms′ tumor, Ewing′s sarcoma, and certain primitive myeloid malignancies, making NCAM monoclonal antibody (C5.9) recommended for cancer research and diagnostics. anti-NCAM antibody (C5.9) assists researchers in elucidating the mechanisms underlying cell adhesion, neural network formation, and the progression of various neuro-related cancers.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    NCAM/CD56 Antibody (2Q692)

    sc-71647
    200 µg/ml
    $322.00

    NCAM/CD56 Antibody (2Q692): m-IgG Fc BP-HRP Bundle

    sc-539386
    200 µg Ab; 10 µg BP
    $361.00

    NCAM/CD56 Antibody (2Q692): m-IgG1 BP-HRP Bundle

    sc-541453
    200 µg Ab; 20 µg BP
    $361.00

    Can NCAM (2Q692): sc-71647 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Asked by: AbPolly
    Thank you for your question. Yes, NCAM (2Q692): sc-71647 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 4 out of 5 by from GreatGreat, strong band by WB in human NCAM transfected 293T whole cell lysates. -SCBT QC
    Date published: 2015-04-08
    Rated 4 out of 5 by from Worked with t293T whole cell lysate by WBWorked with t293T whole cell lysate by WB with a little week signal. -SCBT QC
    Date published: 2014-03-16
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    NCAM/CD56 Antibody (2Q692) is rated 4.0 out of 5 by 2.
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