N6AMT2 Antibody (H-3): sc-390240
- N6AMT2 Antibody (H-3) is a mouse monoclonal IgG2b κ N6AMT2 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 71-103 near the N-terminus of N6AMT2 of human origin
- N6AMT2 Antibody (H-3) is recommended for detection of N6AMT2 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-N6AMT2 Antibody (H-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for N6AMT2 Antibody (H-3) for WB applications. These reagents are now offered in bundles with N6AMT2 Antibody (H-3) (see ordering information below).
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SEE ALSO...
N6AMT2 Antibody (H-3) is a mouse monoclonal IgG2b kappa light chain antibody that detects N6AMT2 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). N6AMT2 (H-3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. N6AMT2, also known as N-6 adenine-specific DNA methyltransferase 2 or ESP13, plays a crucial role in regulating gene expression through DNA methylation, specifically targeting adenine residues. This post-translational modification is vital for maintaining genomic stability and regulating cellular processes such as differentiation and development. Aberrant methylation patterns have been implicated in various diseases, including cancer, making N6AMT2 a significant target for research in epigenetics and tumor biology. N6AMT2 is encoded on human chromosome 13q12.11, a region that contains several important tumor suppressor genes, including BRCA2 and RB1, which are associated with breast cancer susceptibility and retinoblastoma, respectively. Understanding N6AMT2 function and regulation can provide insights into disease mechanisms and therapeutic targets.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
N6AMT2 Antibody (H-3) References:
- The DNA sequence and analysis of human chromosome 13. | Dunham, A., et al. 2004. Nature. 428: 522-8. PMID: 15057823
- Non-disjunction of chromosome 13. | Bugge, M., et al. 2007. Hum Mol Genet. 16: 2004-10. PMID: 17584770
- Variable expressivity in Patau syndrome is not all related to trisomy 13 mosaicism. | Hsu, HF. and Hou, JW. 2007. Am J Med Genet A. 143A: 1739-48. PMID: 17603803
- The origin of trisomy 13. | Hall, HE., et al. 2007. Am J Med Genet A. 143A: 2242-8. PMID: 17853475
- Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture. | Hassler, M., et al. 2007. Mol Cell. 28: 371-85. PMID: 17996702
- BRCA2: a universal recombinase regulator. | Thorslund, T. and West, SC. 2007. Oncogene. 26: 7720-30. PMID: 18066084
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N6AMT2 Antibody (H-3) | sc-390240 | 200 µg/ml | $322.00 | |||
N6AMT2 Antibody (H-3): m-IgG Fc BP-HRP Bundle | sc-530102 | 200 µg Ab; 10 µg BP | $361.00 | |||
N6AMT2 Antibody (H-3): m-IgGκ BP-HRP Bundle | sc-523460 | 200 µg Ab, 40 µg BP | $361.00 | |||
N6AMT2 Antibody (H-3): m-IgG2b BP-HRP Bundle | sc-550165 | 200 µg Ab; 10 µg BP | $361.00 | |||
N6AMT2 Antibody (H-3) AC | sc-390240 AC | 500 µg/ml, 25% agarose | $424.00 | |||
N6AMT2 Antibody (H-3) HRP | sc-390240 HRP | 200 µg/ml | $322.00 | |||
N6AMT2 Antibody (H-3) FITC | sc-390240 FITC | 200 µg/ml | $336.00 | |||
N6AMT2 Antibody (H-3) PE | sc-390240 PE | 200 µg/ml | $349.00 | |||
N6AMT2 Antibody (H-3) Alexa Fluor® 488 | sc-390240 AF488 | 200 µg/ml | $364.00 | |||
N6AMT2 Antibody (H-3) Alexa Fluor® 546 | sc-390240 AF546 | 200 µg/ml | $364.00 | |||
N6AMT2 Antibody (H-3) Alexa Fluor® 594 | sc-390240 AF594 | 200 µg/ml | $364.00 | |||
N6AMT2 Antibody (H-3) Alexa Fluor® 647 | sc-390240 AF647 | 200 µg/ml | $364.00 | |||
N6AMT2 Antibody (H-3) Alexa Fluor® 680 | sc-390240 AF680 | 200 µg/ml | $364.00 | |||
N6AMT2 Antibody (H-3) Alexa Fluor® 790 | sc-390240 AF790 | 200 µg/ml | $364.00 | |||
N6AMT2 (H-3) Neutralizing Peptide | sc-390240 P | 100 µg/0.5 ml | $69.00 |