N-Myc Antibody (2): sc-142
- N-Myc Antibody (2) is a mouse monoclonal IgG2a, cited in 15 publications, provided at 200 µg/ml
- epitope mapping at residues 327-339 of N-Myc of human origin
- Anti-N-Myc Antibody (2) is recommended for detection of N-Myc p67 of mouse, rat and human origin by WB, IP and IF
- Anti-N-Myc Antibody (2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for N-Myc Antibody (2). This work is in progress.
QUICK LINKS
N-Myc Antibody (2) is a mouse monoclonal IgG2a antibody that detects N-Myc p67 in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF) applications. Anti-N-Myc antibody (2) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. N-Myc, a member of the Myc family of oncogenes, plays a crucial role in cell proliferation, differentiation, and apoptosis, making N-Myc a significant factor in cancer biology. N-Myc amplification is particularly relevant in neuroblastomas, where N-Myc has been shown to correlate with disease progression, highlighting N-Myc′s potential as a biomarker for diagnosis and prognosis. Structurally, N-Myc is a nuclear phosphoprotein that undergoes rapid degradation, with a half-life of approximately 30 minutes in vivo, which is essential for regulating N-Myc activity and preventing uncontrolled cell growth. N-Myc′s ability to bind DNA in a sequence-specific manner, following dimerization with the Max protein, underscores N-Myc′s importance in transcriptional regulation and oncogenic processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Myc Antibody (2) | sc-142 | 200 µg/ml | $316.00 | |||
N-Myc Antibody (2) AC | sc-142 AC | 500 µg/ml, 25% agarose | $416.00 | |||
N-Myc Antibody (2) HRP | sc-142 HRP | 200 µg/ml | $316.00 | |||
N-Myc Antibody (2) FITC | sc-142 FITC | 200 µg/ml | $330.00 | |||
N-Myc Antibody (2) PE | sc-142 PE | 200 µg/ml | $343.00 | |||
N-Myc Antibody (2) Alexa Fluor® 488 | sc-142 AF488 | 200 µg/ml | $357.00 | |||
N-Myc Antibody (2) Alexa Fluor® 546 | sc-142 AF546 | 200 µg/ml | $357.00 | |||
N-Myc Antibody (2) Alexa Fluor® 594 | sc-142 AF594 | 200 µg/ml | $357.00 | |||
N-Myc Antibody (2) Alexa Fluor® 647 | sc-142 AF647 | 200 µg/ml | $357.00 | |||
N-Myc Antibody (2) Alexa Fluor® 680 | sc-142 AF680 | 200 µg/ml | $357.00 | |||
N-Myc Antibody (2) Alexa Fluor® 790 | sc-142 AF790 | 200 µg/ml | $357.00 |