Mx1 Antibody (C-12): sc-271399
- Mx1 Antibody (C-12) is a mouse monoclonal IgM κ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 171-455 mapping within an internal region of Mx1 of human origin
- recommended for detection of Mx1 of human origin by WB, IP, IF and ELISA
- See Mx1/2/3 (C-1): sc-166412 for Mx1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGκ BP-HRP is the preferred secondary detection reagent for Mx1 Antibody (C-12) for WB applications. This reagent is now offered in a bundle with Mx1 Antibody (C-12) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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Mx1 Antibody (C-12) is a mouse monoclonal IgM antibody that detects Mx1 in humans through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Mx1, also known as myxovirus resistance protein 1, plays a crucial role in the immune response by providing selective resistance to viral infections, particularly the highly pathogenic H5N1 influenza virus. Mx1 is primarily localized in the nucleus, where interferon-alpha and interferon-beta induce Mx1, leading to the transcriptional activation of genes that inhibit viral replication. Nuclear localization of Mx1 allows for a rapid response to viral threats, effectively blocking viral replication before spreading. Additionally, Mx1 interacts with various cellular factors that enhance antiviral activity, making Mx1 a vital component of the innate immune system. anti-Mx1 antibody (C-12) is an essential tool for researchers studying viral pathogenesis and the mechanisms of antiviral immunity.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Mx1 Antibody (C-12) | sc-271399 | 200 µg/ml | $316.00 | |||
Mx1 Antibody (C-12): m-IgGκ BP-HRP Bundle | sc-534948 | 200 µg Ab; 40 µg BP | $354.00 |