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The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3). The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major com-ponent of various mucus gels and is broadly expressed in normal and tumor cells.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
I need to use an antibody to detect the protein in samples of monkey origin. Do you know if sc-59859: Mucin 2 (B306.1) mouse monoclonal antibody will work?
Asked by: Professor Griffin
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2018-09-29
Auriez-vous l'exemple d'un résultat de western-blot ayant fonctionné contre une Mucin2 (mouse) ?
J'ai déja un anticorps santa cruz anti mucin2 mais celui ci ne fonctionne qu'en IF. Je cherche celui qui me permettra de la détecter en WB.
Asked by: Matthias
Merci pour votre question. L'anticorps Mucin 2 (B306.1): sc-59859 est recommandé pour la détection de Mucin 2 de souris, rat et humaine par les techniques de Western Blot, IF and IHC(P). Nous n'avons malheureusement pas d'image de résultats en Western Blot pour cet anticorps. (PMID: 21278735 pour la détection de Mucin 2 de souris). Cependant, nous offrons une garantie valable pendant un an à partir de la date d'achats pour les applications et espèces recommandées. Ainsi, si vous rencontrez des difficultés avec cet anticorps et que celui-ci ne devait pas fonctionner suivant nos recommandations, veuillez nous contacter par téléphone
+49 6221 45 030 ou par email à [email protected]
Thank you for your question. The antibody Mucin 2 (B306.1): sc-59859 is recommended for detection of Mucin 2 of mouse, rat and human origin by WB, IF and IHC(P). We currently do not have a picture available for this antibody in Western Blot. However, we offer a product warranty of one year from the date of purchase for the recommended applications and species. Therefore, if you are experiencing some issues with this antibody, please contact us by phone +49 6221 45 030 or by email at [email protected] We also list one citation for the use of this antibody on mouse samples: PMID: 21278735
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