MTUS1 Antibody (A-4): sc-393120
- MTUS1 Antibody (A-4) is a mouse monoclonal IgG2b κ MTUS1 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 836-1135 mapping near the C-terminus of MTUS1 of human origin
- MTUS1 Antibody (A-4) is recommended for detection of MTUS1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-MTUS1 Antibody (A-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MTUS1 Antibody (A-4). This work is in progress.
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MTUS1 Antibody (A-4) is a mouse monoclonal IgG2b kappa light chain antibody that detects MTUS1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MTUS1 (A-4) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. MTUS1 protein, also known as mitochondrial tumor suppressor 1 or ATIP (angiotensin-II type 2 receptor-interacting protein), plays a crucial role in cellular signaling and tumor suppression, with highest expression found in brain tissues. Notably, MTUS1 is involved in regulating angiotensin-II type 2 receptor (AT2), where MTUS1 interacts with AT2′s C-terminal tail to inhibit growth factor-induced extracellular signal-regulated kinase 2 activation and subsequent cell proliferation. This interaction maintains cellular homeostasis and prevents uncontrolled cell growth, which can lead to conditions such as hepatocellular carcinoma (HCC). MTUS1 exhibits a predominantly hydrophilic nature, characterized by a large coiled-coil domain and two leucine zipper motifs, which are essential for structural integrity and functional interactions. Additionally, MTUS1 is produced in five transcript variants through alternative splicing, each with distinct cellular localizations and potential roles in various cellular processes, further underscoring MTUS1′s importance in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MTUS1 Antibody (A-4) | sc-393120 | 200 µg/ml | $322.00 | |||
MTUS1 Antibody (A-4) AC | sc-393120 AC | 500 µg/ml, 25% agarose | $424.00 | |||
MTUS1 Antibody (A-4) HRP | sc-393120 HRP | 200 µg/ml | $322.00 | |||
MTUS1 Antibody (A-4) FITC | sc-393120 FITC | 200 µg/ml | $336.00 | |||
MTUS1 Antibody (A-4) PE | sc-393120 PE | 200 µg/ml | $349.00 | |||
MTUS1 Antibody (A-4) Alexa Fluor® 488 | sc-393120 AF488 | 200 µg/ml | $364.00 | |||
MTUS1 Antibody (A-4) Alexa Fluor® 546 | sc-393120 AF546 | 200 µg/ml | $364.00 | |||
MTUS1 Antibody (A-4) Alexa Fluor® 594 | sc-393120 AF594 | 200 µg/ml | $364.00 | |||
MTUS1 Antibody (A-4) Alexa Fluor® 647 | sc-393120 AF647 | 200 µg/ml | $364.00 | |||
MTUS1 Antibody (A-4) Alexa Fluor® 680 | sc-393120 AF680 | 200 µg/ml | $364.00 | |||
MTUS1 Antibody (A-4) Alexa Fluor® 790 | sc-393120 AF790 | 200 µg/ml | $364.00 |