MTHFS Antibody (D-11): sc-390786
- MTHFS Antibody (D-11) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 129-157 of MTHFS of human origin
- recommended for detection of MTHFS of mouse, rat and human origin, and LOC100039707 of mouse origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for MTHFS Antibody (D-11) for WB applications. These reagents are now offered in bundles with MTHFS Antibody (D-11) (see ordering information below).
QUICK LINKS
SEE ALSO...
MTHFS Antibody (D-11) is a mouse monoclonal IgG1 antibody that detects MTHFS in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MTHFS, or 5-formyltetrahydrofolate cyclo-ligase, is a crucial cytosolic protein that plays a significant role in the formate metabolic process, accounting for up to thirty percent of a cell′s cytoplasmic folate derivatives. MTHFS, which requires a magnesium cofactor, catalyzes the ATP-dependent conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a vital step in the folate metabolism pathway. Folate is essential for DNA replication, and a deficiency in this molecule can lead to various disease states, including anemia and neural tube defects. During DNA replication, 5,10-methenyltetrahydrofolate is oxidized, and MTHFS is responsible for resetting this molecule, thereby ensuring the continuity of the replication process. Anti-MTHFS antibody (D-11) is an invaluable tool for researchers studying folate metabolism and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MTHFS Antibody (D-11) | sc-390786 | 200 µg/ml | $322.00 | |||
MTHFS Antibody (D-11): m-IgG Fc BP-HRP Bundle | sc-540852 | 200 µg Ab; 10 µg BP | $361.00 | |||
MTHFS Antibody (D-11): m-IgG1 BP-HRP Bundle | sc-542417 | 200 µg Ab; 20 µg BP | $361.00 | |||
MTHFS (D-11) Neutralizing Peptide | sc-390786 P | 100 µg/0.5 ml | $69.00 |