MTHFD1L Antibody (D-7): sc-515706

MTHFD1L Antibody (D-7) is a mouse monoclonal IgG1 antibody that detects methylenetetrahydrofolate dehydrogenase 1-like (MTHFD1L) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MTHFD1L is a 978-amino acid mitochondrial protein that plays a crucial role in folate metabolism via the tetrahydrofolate pathway, which is essential for the synthesis of nucleotides and amino acids. MTHFD1L exists in two isoforms and is expressed in various tissues, highlighting its importance in cellular metabolism. Notably, MTHFD1L has been implicated in colorectal carcinogenesis, where MTHFD1L may provide a growth advantage to cancer-transformed cells, making MTHFD1L a significant target for cancer research. MTHFD1L′s ability to participate in critical metabolic processes underscores its relevance in both normal physiology and disease states, particularly in cancer development. Anti-MTHFD1L antibody (D-7) is an invaluable tool for researchers investigating the role of folate metabolism in health and disease.

The preferred MTHFD1/1L antibody is MTHFD1/1L Antibody (D-9): sc-376722.