MTHFD1L Antibody (D-7) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
raised against amino acids 73-178 mapping near the N-terminus of MTHFD1L of human origin
recommended for detection of MTHFD1L of human origin by WB, IP, IF and ELISA
m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MTHFD1L Antibody (D-7) for WB applications. These reagents are now offered in bundles with MTHFD1L Antibody (D-7) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) is a 935-amino acid, folate-dependent protein that is responsible for the consecutive interconversion of tetrahydrofolate derivatives which drive the synthesis of purine, methionine and thymidylate. MTHFD1 functions as a homodimer consisting of two major domains; an N-terminal domain containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain in the C-terminus. Mutations in the MTHFD1 gene in pregnant women are associated with an increased risk of giving birth to a child with a neural tube defect, along with a possible risk of decreased embryo survival. MTHFD1L (methylenetetrahydrofolate dehydrogenase 1-like) is a 978 amino acid mitochondrial protein that is expressed in a variety of tissues and, like MTHFD1, functions in folate metabolism via the tetrahydrofolate pathway. MTHFD1L exists as two isoforms and may be associated with colorectal carcinogenesis, possibly conferring a growth advantage to cancer-transformed cells.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.