MMP-13 Antibody (C-3): sc-515284

MMP-13 Antibody (C-3) is a mouse monoclonal IgG1 kappa light chain antibody designed to detect matrix metalloproteinase-13 (MMP-13), also known as collagenase-3, with exceptional accuracy in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA) applications. Raised against amino acids 242-471 at the C-terminus of human MMP-13, anti-MMP-13 antibody (C-3) specifically recognizes MMP-13 from human sources, ensuring no cross-reactivity with other matrix metalloproteinases and providing reliable results for your research. MMP-13 is predominantly localized in the extracellular matrix, where MMP-13 plays a crucial role in the degradation of collagen types I, II, and III, facilitating essential processes such as fetal bone development, adult bone remodeling, and tissue repair. This extracellular localization is vital for MMP-13′s function in remodeling the extracellular environment, which is essential for normal physiological processes and is also implicated in pathological conditions like cancer metastasis and osteoarthritis, where excessive matrix degradation occurs. By enabling precise detection and localization of MMP-13, anti-MMP-13 antibody (C-3) supports advanced studies into the mechanisms of tissue remodeling and the progression of various diseases. Available in both non-conjugated and multiple conjugated forms, including horseradish peroxidase (HRP), fluorescein isothiocyanate (FITC), phycoerythrin (PE), and Alexa Fluor® conjugates, MMP-13 (C-3) antibody offers versatility for diverse experimental setups.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-MMP-13 Antibody (C-3) has 38 citations in a variety of scientific publications.

Primary antibodies like Anti-MMP-13 Antibody (C-3) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

MMP-13 Antibody (C-3) Specifications

Alternate Product Name: MMP-13

Product Clone Name: C-3

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 242-471

Epitope Target: MMP-13

Epitope Species: human

Product Reactivity/Detection: MMP-13

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 38 citations in various scientific publications

Available Conjugates/Forms for MMP-13 Antibody (C-3): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred MMP-13 antibody is MMP-13 Antibody (MM0019-12E10): sc-101564.