Date published: 2026-4-24

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MMP-12 Antibodies

Santa Cruz Biotechnology provides a broad selection of MMP-12 Antibodies for research focused on matrix metalloproteinase-12. MMP-12 Antibodies are available for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Matrix metalloproteinase-12 is a crucial enzyme involved in the degradation of extracellular matrix components, playing a significant role in tissue remodeling and inflammation. Its dysregulation has been implicated in various pathological conditions, including chronic obstructive pulmonary disease (COPD) and cancer metastasis. Understanding matrix metalloproteinase-12 function is essential for developing therapeutic strategies targeting these diseases. Research has shown that matrix metalloproteinase-12 expression levels can serve as important biomarkers in disease progression. Recent studies have highlighted the importance of matrix metalloproteinase-12 in immune cell recruitment and inflammatory responses. Matrix metalloproteinase-12 has emerged as a potential therapeutic target in multiple disease models. Santa Cruz Biotechnology monoclonal antibodies for matrix metalloproteinase-12 support researchers worldwide in advancing scientific understanding of disease mechanisms and potential treatments.

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MMP-12 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

MMP-12 Antibody (A-2)

sc-133151mouse IgG2b171-470 (h)WB, IP, IF, ELISAh
4
(3)

MMP-12 Antibody (G-2)

sc-390863mouse IgG1 κ438-453 (m)WB, IP, IF, ELISAm, r, h
13
(1)

MMP-12 Antibody (H-9)

sc-390284mouse IgG2a κ429-463 (m)WB, IP, IF, ELISAm, r

new

(1)

MMP-12 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MMP-12 CRISPR/Cas9 KO Plasmid (h)

sc-401853hGene KnockoutGFP0
(0)

MMP-12 HDR Plasmid (h)

sc-401853-HDRhHomology Directed RepairPuromycin0
(0)

MMP-12 CRISPR/Cas9 KO Plasmid (m)

sc-421667mGene KnockoutGFP
1
(0)

MMP-12 HDR Plasmid (m)

sc-421667-HDRmHomology Directed RepairPuromycin
1
(0)

MMP-12 CRISPR Activation Products

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MMP-12 CRISPR Activation Plasmid (h)

sc-401853-ACThGene ActivationPuro, Blast, Hygro0
(0)

MMP-12 CRISPR Activation Plasmid (h2)

sc-401853-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

MMP-12 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MMP-12 siRNA (h)

sc-41557hGene SilencingN/A
2
(0)

MMP-12 shRNA Plasmid (h)

sc-41557-SHhGene SilencingPuromycin
2
(0)

MMP-12 shRNA (h) Lentiviral Particles

sc-41557-VhGene SilencingPuromycin
2
(0)

MMP-12 siRNA (m)

sc-41558mGene SilencingN/A0
(0)

MMP-12 shRNA Plasmid (m)

sc-41558-SHmGene SilencingPuromycin0
(0)

MMP-12 shRNA (m) Lentiviral Particles

sc-41558-VmGene SilencingPuromycin0
(0)