MMP-12 Antibody (G-2) is a mouse monoclonal IgG1 (kappa light chain) provided at 200 µg/ml
specific for an epitope mapping between amino acids 438-453 near the C-terminus of MMP-12 of mouse origin
Anti-MMP-12 Antibody (G-2) is recommended for detection of MMP-12 of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-MMP-12 Antibody (G-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
blocking peptide, sc-390863 P
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of MMP-12 (G-2): sc-390863.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-12 (also designated macrophage metalloelastase) is produced in alveolar macrophages and degrades elastin. MMP-12 may contribute to elastin degradation occurring in granulomatous skin diseases and may also participate in macrophage migration through the epidermal and vascular basement membranes in inflammatory disorders.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Does this antibody target the pro-form or active form of Mmp12 or both?
Asked by: Zhipeng
Thank you for your question. The zymogen form for MMP-12 is about ~54 kDa, which is activated to the 45-48 kDa form, which further breaks down to a cascade of active forms and resulting in a common 22 kDa form. Which form you will see depends on what form is present in your sample. Our data with this antibody generally shows the active 48kDa form.
Answered by: Tech Service
Date published: 2019-10-08
I am write in asking for how to receive FREE 10 µg sample of MMP-12 (G-2): sc-390863.
I want to give a try before buying some for my research
Asked by: YuanCao
Thank you for your question. Please contact one of our authorized distributors in Australia to request a free 10 µg sample of this monoclonal antibody. Please use the link below to search for their contact information on our website.
Answered by: Technical Support
Date published: 2017-10-12
What application is the blocking peptide sc-390863 P appropriate for?
Asked by: Professor Griffin
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here:
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn