MKX Antibody (C-5): sc-515878
- MKX Antibody (C-5) is a mouse monoclonal IgG2b κ MKX antibody, cited in 4 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 196-215 within an internal region of MKX of human origin
- MKX Antibody (C-5) is recommended for detection of MKX of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-MKX Antibody (C-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for Gel Supershift and ChIP applications (sc-515878 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MKX Antibody (C-5) for WB applications. These reagents are now offered in bundles with MKX Antibody (C-5) (see ordering information below).
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SEE ALSO...
MKX Antibody (C-5) is a mouse monoclonal IgG2b kappa light chain antibody that detects MKX protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MKX (C-5) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. MKX protein, also known as Homeobox protein Mohawk, is a 352 amino acid nuclear protein that plays a crucial role as a morphogenetic regulator of cell adhesion, influencing the development and maintenance of various tissues. MKX belongs to the TALE/IRO homeobox family and features a homeobox DNA-binding domain, which is essential for its function in regulating gene expression during embryonic development. MKX is located on human chromosome 10, a region that contains over 1,200 genes and represents nearly 4.5% of the human genome. Notably, mutations in genes on chromosome 10 have been linked to several genetic disorders, including Charcot-Marie-Tooth disease and Jackson-Weiss syndrome, highlighting MKX′s importance in developmental biology and potential implications in disease mechanisms.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
MKX Antibody (C-5) References:
- Molecular cell biology of Charcot-Marie-Tooth disease. | Berger, P., et al. 2002. Neurogenetics. 4: 1-15. PMID: 12030326
- The DNA sequence and comparative analysis of human chromosome 10. | Deloukas, P., et al. 2004. Nature. 429: 375-81. PMID: 15164054
- Comparative mapping of human chromosome 10 to pig chromosomes 10 and 14. | Nonneman, D. and Rohrer, GA. 2004. Anim Genet. 35: 338-43. PMID: 15265077
- Roles of FGF signaling in skeletal development and human genetic diseases. | Chen, L. and Deng, CX. 2005. Front Biosci. 10: 1961-76. PMID: 15769677
- Comprehensive analysis of animal TALE homeobox genes: new conserved motifs and cases of accelerated evolution. | Mukherjee, K. and Bürglin, TR. 2007. J Mol Evol. 65: 137-53. PMID: 17665086
- First report of ovarian dysgerminoma in Cowden syndrome with germline PTEN mutation and PTEN-related 10q loss of tumor heterozygosity. | Cho, MY., et al. 2008. Am J Surg Pathol. 32: 1258-64. PMID: 18594467
- Genetic determinants of facial clefting: analysis of 357 candidate genes using two national cleft studies from Scandinavia. | Jugessur, A., et al. 2009. PLoS One. 4: e5385. PMID: 19401770
- Assignment1 of phosphotriesterase-related gene (PTER) to human chromosome band 10p12 by in situ hybridization. | Alimova-Kost, MV., et al. 1998. Cytogenet Cell Genet. 83: 16-7. PMID: 9925913
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MKX Antibody (C-5) | sc-515878 | 200 µg/ml | $316.00 | |||
MKX Antibody (C-5): m-IgG Fc BP-HRP Bundle | sc-531545 | 200 µg Ab; 10 µg BP | $354.00 | |||
MKX Antibody (C-5): m-IgGκ BP-HRP Bundle | sc-525261 | 200 µg Ab, 40 µg BP | $354.00 | |||
MKX Antibody (C-5): m-IgG2b BP-HRP Bundle | sc-550297 | 200 µg Ab; 10 µg BP | $354.00 | |||
MKX Antibody (C-5) X | sc-515878 X | 200 µg/0.1 ml | $316.00 | |||
MKX Antibody (C-5) AC | sc-515878 AC | 500 µg/ml, 25% agarose | $416.00 | |||
MKX Antibody (C-5) HRP | sc-515878 HRP | 200 µg/ml | $316.00 | |||
MKX Antibody (C-5) FITC | sc-515878 FITC | 200 µg/ml | $330.00 | |||
MKX Antibody (C-5) PE | sc-515878 PE | 200 µg/ml | $343.00 | |||
MKX Antibody (C-5) Alexa Fluor® 488 | sc-515878 AF488 | 200 µg/ml | $357.00 | |||
MKX Antibody (C-5) Alexa Fluor® 546 | sc-515878 AF546 | 200 µg/ml | $357.00 | |||
MKX Antibody (C-5) Alexa Fluor® 594 | sc-515878 AF594 | 200 µg/ml | $357.00 | |||
MKX Antibody (C-5) Alexa Fluor® 647 | sc-515878 AF647 | 200 µg/ml | $357.00 | |||
MKX Antibody (C-5) Alexa Fluor® 680 | sc-515878 AF680 | 200 µg/ml | $357.00 | |||
MKX Antibody (C-5) Alexa Fluor® 790 | sc-515878 AF790 | 200 µg/ml | $357.00 |