
MIST1 Antibody (1H1) is a mouse monoclonal IgG1 antibody that detects MIST1 in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. MIST1, also known as BHLHB8, is a 189 amino acid nuclear protein predominantly expressed in the liver, brain, skeletal muscle, and spleen, where MIST1 plays a crucial role in regulating gene expression during development. MIST1 contains a basic helix-loop-helix (bHLH) domain, which allows MIST1 to bind to E-box motifs in the promoter or enhancer regions of various developmentally regulated genes, functioning as either a transcriptional activator or repressor. Notably, MIST1 acts as a repressor of MyoD, a key protein involved in muscle cell differentiation, thereby ensuring that myoblast populations remain undifferentiated and available for muscle development. Additionally, MIST1 is essential for the proper regulation of mammary gland development, highlighting MIST1′s importance in both muscle and epithelial cell biology. Anti-MIST1 antibody (1H1) is an invaluable tool for researchers studying these critical biological processes and the underlying mechanisms of muscle and mammary gland development.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MIST1 Antibody (1H1) | sc-80983 | 200 µg/ml | $322.00 | |||
MIST1 Antibody (1H1): m-IgG Fc BP-HRP Bundle | sc-539578 | 200 µg Ab; 10 µg BP | $361.00 | |||
MIST1 Antibody (1H1): m-IgG1 BP-HRP Bundle | sc-541570 | 200 µg Ab; 20 µg BP | $361.00 |