MIC2 Antibody (1C3): sc-53898
- MIC2 Antibody (1C3) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against cells from stem T-cell leukemia of human origin
- recommended for detection of MIC2 of human origin by WB, IP, IF and IHC(P)
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MIC2 Antibody (1C3) for WB and IHC(P) applications. These reagents are now offered in bundles with MIC2 Antibody (1C3) (see ordering information below).
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SEE ALSO...
MIC2 Antibody (1C3) is a mouse monoclonal IgG1 antibody that detects MIC2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. MIC2, also known as CD99, is a critical T cell surface protein that plays a significant role in lymphocyte aggregation, essential for effective immune responses. MIC2 exists in two forms due to alternative splicing: the major form promotes cellular adhesion, while the truncated form inhibits this process. This balance is crucial as MIC2 regulates the interaction between lymphocytes and other cells through the LFA-1/ICAM-1 pathway, influencing immune cell migration and function. Notably, overexpression of the truncated form of MIC2 can lead to downregulation of LFA-1, resulting in cells that exhibit a Hodgkin′s and Reed-Sternberg (H-RS) phenotype, highlighting MIC2′s importance in maintaining normal cell function and morphology. Anti-MIC2 antibody (1C3) serves as an invaluable tool for researchers studying lymphocyte behavior and the underlying mechanisms of immune regulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MIC2 Antibody (1C3) | sc-53898 | 200 µg/ml | $322.00 | |||
MIC2 Antibody (1C3): m-IgG Fc BP-HRP Bundle | sc-537013 | 200 µg Ab; 10 µg BP | $361.00 | |||
MIC2 Antibody (1C3): m-IgGκ BP-HRP Bundle | sc-534193 | 200 µg Ab; 40 µg BP | $361.00 | |||
MIC2 Antibody (1C3): m-IgG1 BP-HRP Bundle | sc-544956 | 200 µg Ab; 20 µg BP | $361.00 |