MHC class Ib Antibody (130): sc-18832
- MHC class Ib Antibody (130) is a Armenian hamster monoclonal IgG MHC class Ib antibody, cited in 2 publications, provided at 200 µg/ml
- raised against recombinant MHC class I-b antigen M3 of mouse origin
- recommended for detection of the murine MHC class 1b molecule H2-M3 of mouse and rat origin by IP and IF
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also provided azide-free for functional blocking of MHC class I-b antigen M3, sc-18832 L, 200 µg/0.1 ml
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MHC class Ib Antibody (130). This work is in progress.
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MHC class Ib Antibody (130) is a hamster monoclonal IgG antibody engineered to recognize the MHC class I-b protein, also known as H2-M3, from both mouse and rat origins. Anti-MHC class Ib antibody (130) is raised against the recombinant MHC class I-b antigen M3 of mouse origin and is highly effective in detecting H2-M3 molecules through immunoprecipitation (IP) and immunofluorescence (IF) techniques. H2-M3, a non-classical MHC class I molecule, plays a pivotal role in the immune system by presenting N-formylated peptides, typically derived from bacterial proteins, to cytotoxic T lymphocytes. This function is crucial for initiating and regulating immune responses against bacterial infections, making the study of H2-M3 essential for understanding immune recognition and pathogen defense mechanisms. MHC class Ib monoclonal antibody (130) is available in both non-conjugated form and various conjugated forms, including phycoerythrin (PE) and fluorescein isothiocyanate (FITC), providing versatility for diverse experimental applications. Anti-MHC class Ib antibody (130) is recommended for researchers investigating antigen presentation, T cell activation, and the complex interactions within the immune response.
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MHC class Ib Antibody (130) References:
- Polymorphism and evolution of HLA class I and II genes and molecules. | Little, AM. and Parham, P. 1999. Rev Immunogenet. 1: 105-23. PMID: 11256568
- Accessory proteins that control the assembly of MHC molecules with peptides. | Van Kaer, L. 2001. Immunol Res. 23: 205-14. PMID: 11444385
- The major histocompatibility complex of the rat (Rattus norvegicus). | Günther, E. and Walter, L. 2001. Immunogenetics. 53: 520-42. PMID: 11685465
- Molecular genetics of the HLA complex. | Fischer, GF. and Mayr, WR. 2001. Wien Klin Wochenschr. 113: 814-24. PMID: 11732117
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MHC class Ib Antibody (130) | sc-18832 | 200 µg/ml | $322.00 | |||
MHC class Ib Antibody (130) FITC | sc-18832 FITC | 200 µg/ml | $336.00 | |||
MHC class Ib Antibody (130) L | sc-18832 L | 200 µg/0.1 ml | $322.00 | |||
MHC class Ib Antibody (130) PE | sc-18832 PE | 200 µg/ml | $349.00 |