MCP-1 Antibody (1A7B8): sc-32819

MCP-1 Antibody (1A7B8) is a mouse monoclonal IgG1 antibody that detects MCP-1 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. MCP-1, also known as CCL2, plays a crucial role in the immune response by mediating the recruitment of monocytes to sites of inflammation, which is vital for effective immune surveillance and tissue repair. This chemokine is primarily secreted by activated T lymphocytes and other immune cells in response to pro-inflammatory cytokines such as interleukin-1, tumor necrosis factor-alpha, and interferon-gamma. The ability of MCP-1 to attract monocytes is particularly important during infection and inflammatory processes, as it facilitates the accumulation of leukocytes at the site of injury or infection, thereby enhancing the body′s defense mechanisms. Additionally, MCP-1 interacts with two distinct receptors, CCR2 and CCR4, which are involved in mediating its effects on various immune cell types. Anti-MCP-1 antibody (1A7B8) is an essential tool for researchers studying the dynamics of immune responses and the role of chemokines in various pathological conditions.

The preferred MCP-1 antibody is MCP-1 Antibody (5J): sc-32771.