MAVS Antibody (E-6): sc-365334
- MAVS Antibody (E-6) is a mouse monoclonal IgG1 κ, cited in 13 publications, provided at 200 µg/ml
- raised against amino acids 1-300 mapping within an N-terminal cytoplasmic domain of MAVS of mouse origin
- MAVS Antibody (E-6) is recommended for detection of MAVS of mouse origin by WB, IP, IF and ELISA
- Anti-MAVS Antibody (E-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MAVS Antibody (E-6) for WB applications. These reagents are now offered in bundles with MAVS Antibody (E-6) (see ordering information below).
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SEE ALSO...
MAVS Antibody (E-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects MAVS protein of mouse origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MAVS (E-6) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. MAVS, or mitochondrial antiviral-signaling protein, is a crucial 540 amino acid protein that plays a significant role in the immune response to viral infections. MAVS protein is primarily located in the outer mitochondrial membrane, where MAVS acts as a signaling hub for the detection of double-stranded viral RNA by proteins such as RIG-I. Proper localization of MAVS protein is essential for function, as MAVS facilitates the activation of downstream signaling pathways that lead to the production of antiviral cytokines, thereby enhancing the host′s immune defense. Additionally, MAVS protein is subject to post-translational modifications, including cleavage by viral proteases, which can inactivate signaling capabilities and hinder the immune response. The presence of three isoforms of MAVS, resulting from alternative splicing, adds another layer of complexity to regulation and function, making anti-MAVS antibody (E-6) a valuable tool for studying the intricate mechanisms of antiviral immunity in mouse models.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MAVS Antibody (E-6) | sc-365334 | 200 µg/ml | $322.00 | |||
MAVS Antibody (E-6): m-IgG Fc BP-HRP Bundle | sc-529353 | 200 µg Ab; 10 µg BP | $361.00 | |||
MAVS Antibody (E-6): m-IgGκ BP-HRP Bundle | sc-522211 | 200 µg Ab, 40 µg BP | $361.00 | |||
MAVS Antibody (E-6): m-IgG1 BP-HRP Bundle | sc-543474 | 200 µg Ab; 20 µg BP | $361.00 | |||
MAVS Antibody (E-6) AC | sc-365334 AC | 500 µg/ml, 25% agarose | $424.00 | |||
MAVS Antibody (E-6) HRP | sc-365334 HRP | 200 µg/ml | $322.00 | |||
MAVS Antibody (E-6) FITC | sc-365334 FITC | 200 µg/ml | $336.00 | |||
MAVS Antibody (E-6) PE | sc-365334 PE | 200 µg/ml | $349.00 | |||
MAVS Antibody (E-6) Alexa Fluor® 488 | sc-365334 AF488 | 200 µg/ml | $364.00 | |||
MAVS Antibody (E-6) Alexa Fluor® 546 | sc-365334 AF546 | 200 µg/ml | $364.00 | |||
MAVS Antibody (E-6) Alexa Fluor® 594 | sc-365334 AF594 | 200 µg/ml | $364.00 | |||
MAVS Antibody (E-6) Alexa Fluor® 647 | sc-365334 AF647 | 200 µg/ml | $364.00 | |||
MAVS Antibody (E-6) Alexa Fluor® 680 | sc-365334 AF680 | 200 µg/ml | $364.00 | |||
MAVS Antibody (E-6) Alexa Fluor® 790 | sc-365334 AF790 | 200 µg/ml | $364.00 |