MAST1 Antibody (G-4): sc-373845
- MAST1 Antibody (G-4) is a mouse monoclonal IgG2b κ MAST1 antibody, cited in 4 publications, provided at 200 µg/ml
- raised against amino acids 777-887 mapping within an internal region of MAST1 of human origin
- MAST1 Antibody (G-4) is recommended for detection of MAST1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-MAST1 Antibody (G-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MAST1 Antibody (G-4) for WB applications. These reagents are now offered in bundles with MAST1 Antibody (G-4) (see ordering information below).
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MAST1 Antibody (G-4) is a mouse monoclonal IgG2b kappa light chain antibody that detects MAST1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-MAST1 antibody (G-4) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. MAST1, also known as microtubule-associated serine/threonine-protein kinase 1, plays a crucial role in cellular signaling by linking the dystrophin/utrophin network with microtubule filaments through interaction with Syntrophin, an adapter protein. This interaction is vital for the structural integrity and function of the dystrophin-associated protein complex, which connects the extracellular matrix to the intracellular cytoskeleton, thereby facilitating the construction and maintenance of postsynaptic structures in both the neuromuscular junction and the central nervous system. Proper functioning of MAST1 is essential for maintaining cellular architecture and signaling pathways, making MAST1 a significant target for research in muscle and neurological disorders.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
MAST1 Antibody (G-4) References:
- Interactions between beta 2-syntrophin and a family of microtubule-associated serine/threonine kinases. | Lumeng, C., et al. 1999. Nat Neurosci. 2: 611-7. PMID: 10404183
- Sast124, a novel splice variant of syntrophin-associated serine/threonine kinase (SAST), is specifically localized in the restricted brain regions. | Yano, R., et al. 2003. Neuroscience. 117: 373-81. PMID: 12614677
- Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases. | Valiente, M., et al. 2005. J Biol Chem. 280: 28936-43. PMID: 15951562
- Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery. | De Angelis, PM., et al. 2006. Mol Cancer. 5: 20. PMID: 16709241
- [Identification of a novel human MAST4 gene, a new member of the microtubule associated serine-threonine kinase family]. | Sun, L., et al. 2006. Mol Biol (Mosk). 40: 808-15. PMID: 17086981
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MAST1 Antibody (G-4) | sc-373845 | 200 µg/ml | $322.00 | |||
MAST1 Antibody (G-4): m-IgG Fc BP-HRP Bundle | sc-529588 | 200 µg Ab; 10 µg BP | $361.00 | |||
MAST1 Antibody (G-4): m-IgGκ BP-HRP Bundle | sc-522529 | 200 µg Ab, 40 µg BP | $361.00 | |||
MAST1 Antibody (G-4): m-IgG2b BP-HRP Bundle | sc-550128 | 200 µg Ab; 10 µg BP | $361.00 | |||
MAST1 Antibody (G-4) AC | sc-373845 AC | 500 µg/ml, 25% agarose | $424.00 | |||
MAST1 Antibody (G-4) HRP | sc-373845 HRP | 200 µg/ml | $322.00 | |||
MAST1 Antibody (G-4) FITC | sc-373845 FITC | 200 µg/ml | $336.00 | |||
MAST1 Antibody (G-4) PE | sc-373845 PE | 200 µg/ml | $349.00 | |||
MAST1 Antibody (G-4) Alexa Fluor® 488 | sc-373845 AF488 | 200 µg/ml | $364.00 | |||
MAST1 Antibody (G-4) Alexa Fluor® 546 | sc-373845 AF546 | 200 µg/ml | $364.00 | |||
MAST1 Antibody (G-4) Alexa Fluor® 594 | sc-373845 AF594 | 200 µg/ml | $364.00 | |||
MAST1 Antibody (G-4) Alexa Fluor® 647 | sc-373845 AF647 | 200 µg/ml | $364.00 | |||
MAST1 Antibody (G-4) Alexa Fluor® 680 | sc-373845 AF680 | 200 µg/ml | $364.00 | |||
MAST1 Antibody (G-4) Alexa Fluor® 790 | sc-373845 AF790 | 200 µg/ml | $364.00 |