MASL1 Antibody (H-1): sc-390556

MASL1 Antibody (H-1) is a mouse monoclonal IgG1 antibody that detects MASL1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MASL1, also known as malignant fibrous histiocytoma amplified sequence 1 (MFHAS1) or LRRC65, is a 1,052 amino acid protein characterized by the presence of 13 leucine-rich repeats (LRRs), which are crucial for mediating protein-protein interactions during the cell cycle. The structure of MASL1, with its hydrophobic α/β horseshoe fold formed by the LRRs, allows MASL1 to effectively accommodate multiple leucine residues, facilitating its role as a structural component in various cellular processes. Ubiquitously expressed, MASL1 is notably upregulated in malignant fibrous histiocytomas, indicating MASL1′s potential involvement in tumorigenesis through the regulation of protein interactions that are essential for cell cycle progression. Furthermore, the gene encoding MASL1 is associated with chromosomal aberrations linked to B-cell lymphoma, underscoring MASL1′s significance in cancer biology and the importance of studying this protein in the context of tumor formation and progression. Anti-MASL1 antibody (H-1) provides a valuable tool for researchers investigating the role of MASL1 in various biological processes and diseases.

The preferred MASL1 antibody is MASL1 Antibody (C-8): sc-514968.