MASL1 Inhibitors
MASL1 inhibitors are a class of chemical compounds that target a specific protein known as Malignant T-cell Amplified Sequence 1 (MASL1). These inhibitors are designed to modulate the activity of MASL1 within cells, which plays a crucial role in various cellular processes. MASL1 itself is a relatively newly discovered protein, and its functions are still being elucidated by researchers. However, its emerging importance in cellular homeostasis and proliferation has made it an intriguing target for drug development, particularly in the context of cancer research.
MASL1 inhibitors are primarily small molecules that have been synthesized and optimized in laboratories for their ability to interact with MASL1. Through a variety of mechanisms, MASL1 inhibitors can disrupt the normal functions of MASL1, which may include its involvement in protein translation and cellular stress responses.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $53.00 $89.00 | 7 | |
Disulfiram can chelate zinc ions, which are essential for the catalytic activity of metalloenzymes, and MFHAS1 possesses a RING domain that coordinates zinc. By chelating zinc, disulfiram may disrupt the structural integrity of MFHAS1. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
Cisplatin forms DNA adducts and thereby activates various signal transduction pathways that can lead to the downregulation of proteins like MFHAS1, affecting its expression indirectly. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Triptolide can inhibit the transcription of a wide range of genes. It may decrease the expression of MFHAS1 by suppressing transcription factors that regulate MFHAS1 gene expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is known to modulate multiple signaling pathways and could alter the expression levels of proteins like MFHAS1 through indirect regulatory mechanisms. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is an inhibitor of MEK, which is part of the MAPK/ERK pathway. Inhibition of this pathway can lead to changes in the expression of several proteins, possibly including MFHAS1. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor that can affect the PI3K/AKT/mTOR pathway, potentially leading to decreased translation of proteins such as MFHAS1. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of JNK, and by inhibiting this pathway, it may influence the stability and expression of various proteins, potentially including MFHAS1. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 is a p38 MAPK inhibitor, and by interfering with this signaling pathway, it may alter the expression or function of proteins like MFHAS1. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Chloroquine can elevate lysosomal pH, which might interfere with the degradation processes of cellular proteins, possibly affecting the turnover of MFHAS1. | ||||||
Olaparib | 763113-22-0 | sc-302017 sc-302017A sc-302017B | 250 mg 500 mg 1 g | $210.00 $305.00 $495.00 | 10 | |
Olaparib is a PARP inhibitor that can influence DNA repair mechanisms, and through complex signaling interplay, it might have an effect on the regulation of protein expression, including MFHAS1. | ||||||