MAGE Antibody (5G152): sc-71536
- MAGE Antibody (5G152) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against a prokaryotic recombinant fusion protein corresponding to the full length MAGE-A1-A1
- recommended for detection of MAGE-1, 2, 3, 4, 6, 10 and 12 of human origin by WB, IP and IF
- m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MAGE Antibody (5G152) for WB applications. These reagents are now offered in bundles with MAGE Antibody (5G152) (see ordering information below).
MAGE Antibody (5G152) is a mouse monoclonal IgG2a antibody that detects MAGE in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-MAGE antibody (5G152) targets the melanoma-associated antigen (MAGE) family, which consists of tumor-rejection antigens recognized by cytotoxic T lymphocytes and is primarily expressed in various tumors while being virtually absent in normal adult tissues, with the notable exceptions of the testis and placenta. The unique expression pattern of MAGE proteins in tumors makes them significant targets for cancer immunotherapy, as they can elicit strong immune responses against cancer cells. Understanding the structure of MAGE proteins is crucial, as they are characterized by a specific arrangement of domains that facilitate their interaction with T cell receptors, thereby enhancing the immune system′s ability to recognize and eliminate tumor cells. The structural integrity of these proteins is vital for their function, as any alterations could impact their recognition by immune cells, potentially leading to immune evasion by tumors. MAGE (5G152) antibody is an essential tool for researchers investigating the role of MAGE proteins in cancer biology and the development of targeted immunotherapies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MAGE Antibody (5G152) | sc-71536 | 200 µg/ml | $322.00 | |||
MAGE Antibody (5G152): m-IgGκ BP-HRP Bundle | sc-534409 | 200 µg Ab; 40 µg BP | $361.00 | |||
MAGE Antibody (5G152): m-IgG2a BP-HRP Bundle | sc-546189 | 200 µg Ab; 10 µg BP | $361.00 |