LYSMD1 Antibody (G-3): sc-514030

LYSMD1 Antibody (G-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects LYSMD1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). LYSMD1 Antibody (G-3) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. LYSMD1, also known as SB145, is a 227 amino acid protein characterized by the presence of one LysM repeat and exists in two alternatively spliced isoforms. LYSMD1 plays a crucial role in the immune response by potentially binding to peptidoglycans, which are essential components of bacterial cell walls, thereby facilitating the recognition and clearance of pathogens. The gene encoding LYSMD1 is located on human chromosome 1, a region associated with numerous diseases, including various cancers and genetic disorders. The significance of LYSMD1 in immune function highlights potential as a target for therapeutic interventions in infectious diseases and immune-related conditions.

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LYSMD1 Antibody (G-3) References:

1. Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.  |  Blackwood, DH., et al. 2001. Am J Hum Genet. 69: 428-33. PMID: 11443544
2. New insights into the evolution of chromosome 1.  |  Weise, A., et al. 2005. Cytogenet Genome Res. 108: 217-22. PMID: 15545733
3. Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody.  |  McClintock, D., et al. 2006. Proc Natl Acad Sci U S A. 103: 2154-9. PMID: 16461887
4. Cell biology: ageing nucleus gets out of shape.  |  Lans, H. and Hoeijmakers, JH. 2006. Nature. 440: 32-4. PMID: 16511477
5. Chromosome 1 abnormalities in multiple myeloma.  |  Marzin, Y., et al. 2006. Anticancer Res. 26: 953-9. PMID: 16619492
6. Lamin A-dependent nuclear defects in human aging.  |  Scaffidi, P. and Misteli, T. 2006. Science. 312: 1059-63. PMID: 16645051
7. Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness.  |  Hennah, W., et al. 2006. Schizophr Bull. 32: 409-16. PMID: 16699061
8. The DNA sequence and biological annotation of human chromosome 1.  |  Gregory, SG., et al. 2006. Nature. 441: 315-21. PMID: 16710414
9. Genomic organization of the selectin family of leukocyte adhesion molecules on human and mouse chromosome 1.  |  Watson, ML., et al. 1990. J Exp Med. 172: 263-72. PMID: 1694218
10. Myeloid cells limit production of antibody-secreting cells after immunization in the lymph node.  |  Fooksman, DR., et al. 2014. J Immunol. 192: 1004-12. PMID: 24376270
11. Microsatellite instability-related prognostic risk score (MSI-pRS) defines a subset of lung squamous cell carcinoma (LUSC) patients with genomic instability and poor clinical outcome.  |  Hu, Z., et al. 2023. Front Genet. 14: 1061002. PMID: 36873930
12. LYSMD proteins promote activation of Rab32-family GTPases for lysosome-related organelle biogenesis.  |  Li, J., et al. 2024. J Cell Biol. 223: PMID: 39078368

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-LYSMD1 Antibody (G-3) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-LYSMD1 Antibody (G-3) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

LYSMD1 Antibody (G-3) Specifications

Alternate Product Name: LYSMD1

Product Clone Name: G-3

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 205-223

Epitope Target: LYSMD1

Epitope Species: human

Product Reactivity/Detection: LYSMD1

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for LYSMD1 Antibody (G-3): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin