Date published: 2026-5-2

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Lyl-1 Antibody (F-9): sc-390277

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Datasheets
  • Lyl-1 Antibody (F-9) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
  • raised against amino acids 199-278 mapping at the C-terminus of Lyl-1 of mouse origin
  • Lyl-1 Antibody (F-9) is recommended for detection of Lyl-1 of mouse origin by WB, IP, IF and ELISA
  • Anti-Lyl-1 Antibody (F-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • TransCruz reagent for ChIP application (sc-390277 X, 200 µg/0.1 ml)
  • m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for Lyl-1 Antibody (F-9) for WB applications. These reagents are now offered in bundles with Lyl-1 Antibody (F-9) (see ordering information below).
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    Lyl-1 Antibody (F-9) is a mouse monoclonal IgG2b kappa light chain antibody that detects Lyl-1 of mouse origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Lyl-1 (F-9) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Lyl-1, also known as lymphoblastic leukemia-derived sequence 1, is a crucial nuclear protein that plays a significant role in regulating hematopoiesis and is implicated in T cell acute leukemia. Lyl-1 is primarily located in the nucleus, where Lyl-1 forms complexes with E2α proteins, facilitating heterodimeric complexes that exhibit unique DNA-binding properties essential for gene regulation in hematolymphoid cells. This nuclear localization allows Lyl-1 to directly influence transcriptional programs critical for normal lymphocyte development and function. Aberrations involving Lyl-1 are associated with chromosomal translocations that lead to T cell acute lymphoblastic leukemia (T-ALL), highlighting Lyl-1′s importance in both normal physiology and disease pathology.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Lyl-1 Antibody (F-9)

    sc-390277
    200 µg/ml
    $322.00

    Lyl-1 Antibody (F-9): m-IgG Fc BP-HRP Bundle

    sc-526142
    200 µg Ab; 10 µg BP
    $361.00

    Lyl-1 Antibody (F-9): m-IgG2b BP-HRP Bundle

    sc-549683
    200 µg Ab; 10 µg BP
    $361.00

    Lyl-1 Antibody (F-9) X

    sc-390277 X
    200 µg/0.1 ml
    $322.00

    Lyl-1 Antibody (F-9) AC

    sc-390277 AC
    500 µg/ml, 25% agarose
    $424.00

    Lyl-1 Antibody (F-9) HRP

    sc-390277 HRP
    200 µg/ml
    $322.00

    Lyl-1 Antibody (F-9) FITC

    sc-390277 FITC
    200 µg/ml
    $336.00

    Lyl-1 Antibody (F-9) PE

    sc-390277 PE
    200 µg/ml
    $349.00

    Lyl-1 Antibody (F-9) Alexa Fluor® 488

    sc-390277 AF488
    200 µg/ml
    $364.00

    Lyl-1 Antibody (F-9) Alexa Fluor® 546

    sc-390277 AF546
    200 µg/ml
    $364.00

    Lyl-1 Antibody (F-9) Alexa Fluor® 594

    sc-390277 AF594
    200 µg/ml
    $364.00

    Lyl-1 Antibody (F-9) Alexa Fluor® 647

    sc-390277 AF647
    200 µg/ml
    $364.00

    Lyl-1 Antibody (F-9) Alexa Fluor® 680

    sc-390277 AF680
    200 µg/ml
    $364.00

    Lyl-1 Antibody (F-9) Alexa Fluor® 790

    sc-390277 AF790
    200 µg/ml
    $364.00

    For Western Blot, is it recommended to use denatured or non-denatured conditions with Lyl-1 (F-9): sc-390277 monoclonal antibody?

    Asked by: jenniferc
    Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
    Answered by: Technical Support
    Date published: 2017-02-27
    • y_2026, m_4, d_29, h_11CST
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    Rated 5 out of 5 by from Satisfactory Western Blot data of LylSatisfactory Western Blot data of Lyl-1 expression in SP2/0 and I-11. -SCBT QC
    Date published: 2015-05-13
    Rated 5 out of 5 by from Nice Western Blot data of LylNice Western Blot data of Lyl-1 expression in human spleen tissue extract and c4 whole cell lysate . -SCBT QC
    Date published: 2013-03-08
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    Lyl-1 Antibody (F-9) is rated 5.0 out of 5 by 2.
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