LXR beta/NER/NR1H2 Antibody (H-8): sc-133221
- LXR beta/NER/NR1H2 Antibody (H-8) is a mouse monoclonal IgG1 κ, cited in 4 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 42-81 near the N-terminus of LXRβ of human origin
- recommended for detection of LXRβ of human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-133221 X, 200 µg/0.1 ml)
- See LXR alpha/beta/NR1H3/NR1H2 (H-7): sc-377260 for LXR beta/NER/NR1H2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for LXR beta/NER/NR1H2 Antibody (H-8) for WB applications. These reagents are now offered in bundles with LXR beta/NER/NR1H2 Antibody (H-8) (see ordering information below).
LXRβ Antibody (H-8) is a mouse monoclonal IgG1 kappa light chain antibody specific to an epitope within amino acids 42-81 near the N-terminus of the liver X receptor beta (LXRβ) in humans, also known as NR1H2. LXRβ is a nuclear receptor that, along with its closely related partner LXRα, plays a key role in regulating cholesterol, fatty acid, and glucose metabolism, especially in hepatocytes and macrophages. This receptor acts as a transcriptional regulator by forming heterodimers with the retinoic X receptor (RXR) in response to ligand binding, influencing gene expression related to lipid homeostasis and inflammation. In addition to responding to ligands like oxysterols, LXRβ is part of the "orphan receptor" family due to its broad ligand reactivity, sharing ligand types with LXRα and displaying high expression in neuronal and endocrine tissues. Functionally, LXRβ′s modulation of lipid metabolism has implications for cellular lipid storage and transport, impacting processes such as atherosclerosis prevention and energy balance. Anti-LXRβ antibody (H-8) is recommended for applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA) in research on metabolic regulation and cholesterol homeostasis.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LXR beta/NER/NR1H2 Antibody (H-8) | sc-133221 | 200 µg/ml | $322.00 | |||
LXR beta/NER/NR1H2 Antibody (H-8): m-IgG Fc BP-HRP Bundle | sc-539868 | 200 µg Ab; 10 µg BP | $361.00 | |||
LXR beta/NER/NR1H2 Antibody (H-8): m-IgG1 BP-HRP Bundle | sc-541754 | 200 µg Ab; 20 µg BP | $361.00 | |||
LXR beta/NER/NR1H2 (H-8) Neutralizing Peptide | sc-133221 P | 100 µg/0.5 ml | $69.00 | |||
LXR beta/NER/NR1H2 Antibody (H-8) X | sc-133221 X | 200 µg/0.1 ml | $322.00 |