LXR Activators
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
T 0901317 | 293754-55-9 | sc-202824 sc-202824A | 10 mg 50 mg | $89.00 $224.00 | 5 | |
T 0901317 is a selective ligand for liver X receptors (LXRs), exhibiting unique interactions that modulate gene expression related to lipid metabolism. Its binding affinity promotes the recruitment of coactivators, enhancing transcriptional activity. This compound influences the regulation of cholesterol homeostasis and fatty acid synthesis through distinct signaling pathways. Additionally, T 0901317's structural features facilitate specific conformational changes in LXR, optimizing receptor functionality and downstream effects. | ||||||
24(S),25-Epoxycholesterol | 77058-74-3 | sc-471354 | 1 mg | $326.00 | ||
24(S),25-Epoxycholesterol acts as a potent liver X receptor (LXR) modulator, engaging in specific molecular interactions that influence lipid metabolism. Its unique epoxide structure allows for selective binding, promoting conformational changes in LXR that enhance its transcriptional activity. This compound plays a critical role in regulating cholesterol and fatty acid biosynthesis by activating distinct signaling cascades, ultimately impacting cellular lipid homeostasis. | ||||||
Acetyl Podocarpic Acid Anhydride | 344327-48-6 | sc-221207 sc-221207A | 1 mg 5 mg | $23.00 $105.00 | ||
Acetyl Podocarpic Acid Anhydride functions as a liver X receptor (LXR) modulator through its unique anhydride structure, which facilitates the formation of acyl-enzyme intermediates. This compound exhibits rapid reaction kinetics, allowing for efficient interaction with LXR, leading to altered gene expression related to lipid metabolism. Its ability to form stable complexes with receptor domains enhances specificity, influencing downstream signaling pathways that regulate metabolic processes. | ||||||
GW3965 | 405911-09-3 | sc-490151 sc-490151A sc-490151B | 10 mg 50 mg 1 g | $260.00 $872.00 $1637.00 | ||
GW3965 is a selective ligand for liver X receptors (LXRs), showcasing a unique ability to modulate gene expression related to lipid metabolism. Its interaction with LXRα and LXRβ promotes the transcription of target genes involved in cholesterol homeostasis and fatty acid synthesis. The compound exhibits distinct binding kinetics, influencing receptor activation and downstream signaling pathways. Additionally, GW3965's structural features enable specific molecular interactions that enhance its selectivity and efficacy in regulating metabolic processes. | ||||||