Date published: 2026-5-1

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LRP130 Antibody (E-12): sc-376657

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Datasheets
  • LRP130 Antibody (E-12) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • raised against amino acids 1007-1306 mapping at the C-terminus of LRP130 of mouse origin
  • recommended for detection of LRP130 of mouse, rat and human origin by WB, IP, IF and ELISA
  • TransCruz reagent for ChIP application (sc-376657 X, 200 µg/0.1 ml)
  • See LRP130 (F-7): sc-166178 for LRP130 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for LRP130 Antibody (E-12) for WB applications. These reagents are now offered in bundles with LRP130 Antibody (E-12) (see ordering information below).
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    LRP130 Antibody (E-12) is a mouse monoclonal IgG1 antibody that detects LRP130 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). LRP130, a leucine-rich protein, plays a crucial role as a cytoplasmic mRNA-binding protein involved in the processing of mitochondrial DNA transcripts, which is essential for maintaining mitochondrial function and energy production within cells. The proper functioning of LRP130 is vital, as defects in the LRPPRC gene that encodes this protein are linked to the French-Canadian type of Leigh syndrome, a severe neurological disorder characterized by lesions in the subcortical region of the brain. Additionally, LRP130 interacts with the low-affinity receptor for leukemia inhibitory factor, initiating an intracellular signaling cascade that can influence various cellular processes. Anti-LRP130 antibody (E-12) serves as an invaluable tool for researchers studying mitochondrial function and related diseases.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    LRP130 Antibody (E-12)

    sc-376657
    200 µg/ml
    $322.00

    LRP130 Antibody (E-12): m-IgG Fc BP-HRP Bundle

    sc-537994
    200 µg Ab; 10 µg BP
    $361.00

    LRP130 Antibody (E-12): m-IgGκ BP-HRP Bundle

    sc-535499
    200 µg Ab; 40 µg BP
    $361.00

    LRP130 Antibody (E-12): m-IgG1 BP-HRP Bundle

    sc-545479
    200 µg Ab; 20 µg BP
    $361.00

    LRP130 Antibody (E-12) X

    sc-376657 X
    200 µg/0.1 ml
    $322.00

    What is the recommended fixation method for immunofluorescence staining with LRP130 (E-12): sc-376657 monoclonal antibody?

    Asked by: Cweed
    Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
    Answered by: Technical Support
    Date published: 2017-02-27
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    Rated 5 out of 5 by from Superb immunofluorescence cytoplasmic stainingSuperb immunofluorescence cytoplasmic staining in methanol-fixed HeLa cells. -SCBT QC
    Date published: 2015-05-05
    Rated 5 out of 5 by from Produced positive Western Blot data of LRP130Produced positive Western Blot data of LRP130 expression in NIH/3T3 whole cell lysate. -SCBT QC
    Date published: 2013-05-20
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    LRP130 Antibody (E-12) is rated 5.0 out of 5 by 2.
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