
LRP130 Antibody (E-12) is a mouse monoclonal IgG1 antibody that detects LRP130 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). LRP130, a leucine-rich protein, plays a crucial role as a cytoplasmic mRNA-binding protein involved in the processing of mitochondrial DNA transcripts, which is essential for maintaining mitochondrial function and energy production within cells. The proper functioning of LRP130 is vital, as defects in the LRPPRC gene that encodes this protein are linked to the French-Canadian type of Leigh syndrome, a severe neurological disorder characterized by lesions in the subcortical region of the brain. Additionally, LRP130 interacts with the low-affinity receptor for leukemia inhibitory factor, initiating an intracellular signaling cascade that can influence various cellular processes. Anti-LRP130 antibody (E-12) serves as an invaluable tool for researchers studying mitochondrial function and related diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LRP130 Antibody (E-12) | sc-376657 | 200 µg/ml | $322.00 | |||
LRP130 Antibody (E-12): m-IgG Fc BP-HRP Bundle | sc-537994 | 200 µg Ab; 10 µg BP | $361.00 | |||
LRP130 Antibody (E-12): m-IgGκ BP-HRP Bundle | sc-535499 | 200 µg Ab; 40 µg BP | $361.00 | |||
LRP130 Antibody (E-12): m-IgG1 BP-HRP Bundle | sc-545479 | 200 µg Ab; 20 µg BP | $361.00 | |||
LRP130 Antibody (E-12) X | sc-376657 X | 200 µg/0.1 ml | $322.00 |