LDH-D Antibody (G-8): sc-374127

LDH-D Antibody (G-8) is a mouse monoclonal IgG2b antibody that detects lactate dehydrogenase D (LDH-D) in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). LDH-D plays a crucial role in cellular metabolism, specifically in the conversion of D-lactate to pyruvate, which is essential for energy production in cells. LDH-D (G-8) antibody targets a protein predominantly located in the mitochondria, where LDH-D participates in the metabolic pathways that generate ATP, the energy currency of the cell. The mitochondrial localization of LDH-D is significant because LDH-D allows for efficient energy production in tissues with high metabolic demands, such as the liver and heart. Additionally, LDH-D exists in two alternatively spliced isoforms, which may have distinct regulatory roles in metabolic processes. LDH-D′s ability to interact with other metabolic enzymes further underscores LDH-D′s importance in maintaining cellular energy homeostasis and responding to metabolic stress. With specific reactivity and versatile applications, anti-LDH-D antibody (G-8) serves as an invaluable tool for researchers studying metabolic pathways and energy regulation in various biological contexts.

The preferred LDH-D antibody is LDH-D Antibody (H-10): sc-374128.