LDH-D Antibody (H-10): sc-374128
- LDH-D Antibody (H-10) is a mouse monoclonal IgG1 κ LDH-D antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 1-195 mapping at the N-terminus of LDH-D of human origin
- LDH-D Antibody (H-10) is recommended for detection of LDH-D of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-LDH-D Antibody (H-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for LDH-D Antibody (H-10) for WB and IHC(P) applications. These reagents are now offered in bundles with LDH-D Antibody (H-10) (see ordering information below).
LDH-D Antibody (H-10) is a mouse monoclonal IgG1 kappa light chain antibody that detects LDH-D protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-LDH-D antibody (H-10) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. LDH-D, also known as D-lactate dehydrogenase, is a 507 amino acid mitochondrial enzyme that plays a crucial role in the metabolism of D-lactate, a byproduct of anaerobic glycolysis. LDH-D helps maintain the balance of D-lactate levels in tissues, which can influence metabolic processes and overall cellular health. LDH-D is expressed in various tissues, with moderate levels found in the liver and heart, and lower levels in the kidney and skeletal muscle, indicating involvement in energy metabolism across different organ systems. Understanding LDH-D function and regulation is essential for elucidating its role in metabolic disorders and developing targeted therapies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
LDH-D Antibody (H-10) References:
- [The role of tumor markers in the treatment of germ cell tumor]. | Niwakawa, M. and Tobisu, K. 2001. Gan To Kagaku Ryoho. 28: 1159-65. PMID: 11525037
- Identification of putative mammalian D-lactate dehydrogenase enzymes. | Flick, MJ. and Konieczny, SF. 2002. Biochem Biophys Res Commun. 295: 910-6. PMID: 12127981
- Properties of human testis-specific lactate dehydrogenase expressed from Escherichia coli. | LeVan, KM. and Goldberg, E. 1991. Biochem J. 273 (Pt 3): 587-92. PMID: 1996957
- Locus determining the human sperm-specific lactate dehydrogenase, LDHC, is syntenic with LDHA. | Edwards, YH., et al. 1987. Dev Genet. 8: 219-32. PMID: 2844458
- Lactate dehydrogenase M-subunit deficiencies: clinical features, metabolic background, and genetic heterogeneities. | Kanno, T. and Maekawa, M. 1995. Muscle Nerve Suppl. 3: S54-60. PMID: 7603529
- Methods for the separation of lactate dehydrogenases and clinical significance of the enzyme. | Kopperschläger, G. and Kirchberger, J. 1996. J Chromatogr B Biomed Appl. 684: 25-49. PMID: 8906464
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LDH-D Antibody (H-10) | sc-374128 | 200 µg/ml | $322.00 | |||
LDH-D Antibody (H-10): m-IgG Fc BP-HRP Bundle | sc-529669 | 200 µg Ab; 10 µg BP | $361.00 | |||
LDH-D Antibody (H-10): m-IgGκ BP-HRP Bundle | sc-522633 | 200 µg Ab, 40 µg BP | $361.00 | |||
LDH-D Antibody (H-10): m-IgG1 BP-HRP Bundle | sc-543629 | 200 µg Ab; 20 µg BP | $361.00 | |||
LDH-D Antibody (H-10) AC | sc-374128 AC | 500 µg/ml, 25% agarose | $424.00 | |||
LDH-D Antibody (H-10) HRP | sc-374128 HRP | 200 µg/ml | $322.00 | |||
LDH-D Antibody (H-10) FITC | sc-374128 FITC | 200 µg/ml | $336.00 | |||
LDH-D Antibody (H-10) PE | sc-374128 PE | 200 µg/ml | $349.00 | |||
LDH-D Antibody (H-10) Alexa Fluor® 488 | sc-374128 AF488 | 200 µg/ml | $364.00 | |||
LDH-D Antibody (H-10) Alexa Fluor® 546 | sc-374128 AF546 | 200 µg/ml | $364.00 | |||
LDH-D Antibody (H-10) Alexa Fluor® 594 | sc-374128 AF594 | 200 µg/ml | $364.00 | |||
LDH-D Antibody (H-10) Alexa Fluor® 647 | sc-374128 AF647 | 200 µg/ml | $364.00 | |||
LDH-D Antibody (H-10) Alexa Fluor® 680 | sc-374128 AF680 | 200 µg/ml | $364.00 | |||
LDH-D Antibody (H-10) Alexa Fluor® 790 | sc-374128 AF790 | 200 µg/ml | $364.00 |