LDH-D Antibody (F-4): sc-373989

LDH-D Antibody (F-4) is a mouse monoclonal IgG2a antibody that detects lactate dehydrogenase D (LDH-D) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). LDH-D is a 507 amino acid mitochondrial protein that plays a crucial role in the metabolism of D-lactate, a byproduct of anaerobic glycolysis, and is part of the D-isomer specific 2-hydroxyacid dehydrogenase family. LDH-D (F-4) antibody facilitates research on the conversion of D-lactate to pyruvate, which is essential for energy production and metabolic homeostasis, particularly in tissues that rely on anaerobic metabolism. LDH-D exists in two alternatively spliced isoforms and exhibits a unique expression pattern, being moderately present in the liver and heart, while lower levels are found in the kidney and skeletal muscle. This specific localization suggests a specialized role for LDH-D in energy metabolism within these tissues, potentially influencing physiological processes such as exercise performance and metabolic disorders. Anti-LDH-D antibody (F-4) serves as an invaluable tool for researchers studying metabolic pathways and related diseases.

The preferred LDH-D antibody is LDH-D Antibody (H-10): sc-374128.