Lck Antibody (D-8): sc-166628
- Lck Antibody (D-8) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against amino acids 1-95 mapping at the N-terminus of Lck of human origin
- recommended for detection of Lck p56 of mouse, rat and human origin by WB, IP, IF and ELISA
- See Lck (3A5): sc-433 for Lck antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Lck Antibody (D-8) for WB applications. These reagents are now offered in bundles with Lck Antibody (D-8) (see ordering information below).
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SEE ALSO...
Lck Antibody (D-8) is a mouse monoclonal IgG2b antibody that detects Lck in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Lck is a crucial member of the Src family of non-receptor tyrosine kinases, which play a vital role in various cellular processes, including T cell activation and signaling. Specifically, Lck is predominantly located in the plasma membrane of T cells, where Lck is essential for initiating T cell receptor (TCR) signaling upon antigen recognition. This localization is critical because Lck phosphorylates key substrates involved in the signaling cascade, leading to T cell activation, proliferation, and differentiation. Proper functioning of Lck is paramount for an effective immune response, and dysregulation of Lck activity can contribute to various immunological disorders and malignancies. anti-Lck antibody (D-8) provides a reliable tool for researchers studying T cell biology and the underlying mechanisms of immune responses, making anti-Lck antibody (D-8) an invaluable asset in both basic and translational research.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lck Antibody (D-8) | sc-166628 | 200 µg/ml | $322.00 | |||
Lck Antibody (D-8): m-IgGκ BP-HRP Bundle | sc-534798 | 200 µg Ab; 40 µg BP | $361.00 | |||
Lck Antibody (D-8): m-IgG2b BP-HRP Bundle | sc-549299 | 200 µg Ab; 10 µg BP | $361.00 |