Date published: 2026-4-26

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Lck Substrates

Santa Cruz Biotechnology now offers a broad range of Lck Substrates for use in various applications. Lck (lymphocyte-specific protein tyrosine kinase) is a crucial enzyme in the Src family kinases, playing an essential role in T-cell receptor (TCR) signaling and immune response regulation. Lck Substrates are critical for studying the enzyme's activity and understanding its role in phosphorylation processes that trigger T-cell activation and differentiation. These substrates allow researchers to investigate how Lck-mediated phosphorylation influences cellular signaling pathways and impacts immune cell function. In scientific research, Lck Substrates are used to explore the regulatory mechanisms of immune responses and to dissect the complex signaling networks involved in T-cell activation. They are invaluable tools for understanding the interactions between Lck and other signaling proteins, facilitating the identification of novel regulatory pathways and potential research targets. Moreover, Lck Substrates are employed in high-throughput screening assays to discover new modulators of Lck activity, aiding in the development of experimental models to examine the dynamics of immune signaling. By providing insights into Lck's role in immune regulation, these substrates enhance our understanding of cellular signaling and its implications in various biological contexts. View detailed information on our available Lck Substrates by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

MEK-1 substrate

sc-3014
0.5 mg
$97.00
5
(0)

MEK-1 substrate functions as a selective Lck modulator, distinguished by its capacity to engage in hydrogen bonding and hydrophobic interactions with key residues in the enzyme's active site. This substrate promotes a conformational shift that inhibits Lck's catalytic activity, impacting T-cell receptor signaling pathways. Its unique reaction kinetics demonstrate a rapid association phase, followed by a slower dissociation, allowing for prolonged modulation of Lck activity in cellular contexts.