Lamin B1 Antibody (B-10): sc-374015
- Lamin B1 Antibody (B-10) is a mouse monoclonal IgG1 κ, cited in 314 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 559-586 at the C-terminus of Lamin B1 of mouse origin
- Anti-Lamin B1 Antibody (B-10) is recommended for detection of Lamin B1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-Lamin B1 Antibody (B-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Lamin B1 Antibody (B-10) for WB applications. These reagents are now offered in bundles with Lamin B1 Antibody (B-10) (see ordering information below).
QUICK LINKS
Lamin B1 Antibody (B-10) is a mouse monoclonal IgG1 kappa light chain antibody that detects Lamin B1 in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Lamin B1 plays a crucial role in maintaining the structural integrity of the nuclear envelope and is a key component of the nuclear lamina, which provides a supportive framework for the nucleus and interacts with chromatin to regulate gene expression. Anti-Lamin B1 antibody (B-10) helps researchers study cellular longevity and stability, as Lamin B1 helps preserve nuclear shape and organization during cell division and in response to various cellular stresses. Additionally, Lamin B1 undergoes several post-translational modifications, including farnesylation and phosphorylation, which are vital for function and regulation. Notably, increased phosphorylation of Lamin B1 has been observed prior to nuclear envelope disintegration, suggesting involvement in the apoptotic process. Lamin B1 (B-10) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, making this antibody a versatile tool for studying nuclear dynamics and apoptosis.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lamin B1 Antibody (B-10) | sc-374015 | 200 µg/ml | $316.00 | |||
Lamin B1 Antibody (B-10): m-IgG Fc BP-HRP Bundle | sc-529634 | 200 µg Ab; 10 µg BP | $354.00 | |||
Lamin B1 Antibody (B-10): m-IgGκ BP-HRP Bundle | sc-522588 | 200 µg Ab, 40 µg BP | $354.00 | |||
Lamin B1 Antibody (B-10) AC | sc-374015 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Lamin B1 Antibody (B-10) HRP | sc-374015 HRP | 200 µg/ml | $316.00 | |||
Lamin B1 Antibody (B-10) FITC | sc-374015 FITC | 200 µg/ml | $330.00 | |||
Lamin B1 Antibody (B-10) PE | sc-374015 PE | 200 µg/ml | $343.00 | |||
Lamin B1 Antibody (B-10) Alexa Fluor® 488 | sc-374015 AF488 | 200 µg/ml | $357.00 | |||
Lamin B1 Antibody (B-10) Alexa Fluor® 546 | sc-374015 AF546 | 200 µg/ml | $357.00 | |||
Lamin B1 Antibody (B-10) Alexa Fluor® 594 | sc-374015 AF594 | 200 µg/ml | $357.00 | |||
Lamin B1 Antibody (B-10) Alexa Fluor® 647 | sc-374015 AF647 | 200 µg/ml | $357.00 | |||
Lamin B1 Antibody (B-10) Alexa Fluor® 680 | sc-374015 AF680 | 200 µg/ml | $357.00 | |||
Lamin B1 Antibody (B-10) Alexa Fluor® 790 | sc-374015 AF790 | 200 µg/ml | $357.00 | |||
Lamin B1 (B-10) Neutralizing Peptide | sc-374015 P | 100 µg/0.5 ml | $68.00 |