Date published: 2026-1-7

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Lamin B1 Activators

Lamin B1 Activators are a class of chemical compounds that have garnered significant attention in the field of molecular biology and cellular research due to their pivotal role in modulating the function of the nuclear envelope, specifically in relation to the protein lamin B1. Lamin B1 is a structural protein found in the inner nuclear membrane of eukaryotic cells, and it plays a crucial role in maintaining nuclear architecture and integrity. Lamin B1 Activators, as the name suggests, are compounds that have the ability to modulate the activity of lamin B1, which, in turn, impacts various cellular processes and functions.

These activators are typically small molecules or peptides that interact with lamin B1, leading to changes in its conformation or function. By binding to lamin B1, these compounds can influence its role in chromatin organization, gene expression, and nuclear stability. Researchers have identified several lamin B1 activators, each with unique mechanisms of action. Some activators promote the proper assembly of lamin B1 within the nuclear lamina, contributing to the maintenance of nuclear structure. Others may enhance lamin B1's interactions with other nuclear components, impacting processes like DNA replication and repair. Understanding the precise mechanisms by which lamin B1 activators function is a topic of ongoing research and holds promise for shedding light on fundamental cellular processes. In summary, Lamin B1 Activators constitute a chemical class that holds immense potential for elucidating the intricate workings of the cell nucleus. Their ability to influence lamin B1, a key player in nuclear organization, makes them valuable tools for researchers seeking to unravel the complexities of cellular biology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol is a natural polyphenol found in grapes and red wine. It has been suggested to activate Lamin B1 by modulating gene expression and promoting cellular health through its antioxidant properties.

N-Acetyl-L-cysteine

616-91-1sc-202232
sc-202232A
sc-202232C
sc-202232B
5 g
25 g
1 kg
100 g
$34.00
$74.00
$270.00
$114.00
34
(1)

N-acetyl cysteine (NAC) is an antioxidant and precursor to the amino acid cysteine. NAC can activate Lamin B1 indirectly by replenishing intracellular glutathione, which plays a role in maintaining the structure and function of the cell nucleus.

Lovastatin

75330-75-5sc-200850
sc-200850A
sc-200850B
5 mg
25 mg
100 mg
$29.00
$90.00
$339.00
12
(1)

Lovastatin is a statin drug used to lower cholesterol. It can activate Lamin B1 by inhibiting the mevalonate pathway, which indirectly affects Lamin B1 prenylation, a process necessary for its function.

Farnesyl thiosalicylic acid

162520-00-5sc-205322
sc-205322A
1 mg
5 mg
$61.00
$82.00
15
(1)

Salirasib is an inhibitor of Ras, a protein associated with cancer. By targeting Ras, it indirectly promotes Lamin B1 stability, as Ras can influence Lamin B1 function in some cellular contexts.

Geranylgeranylacetone

6809-52-5sc-252851
sc-252851A
10 mg
100 mg
$66.00
$158.00
2
(1)

This compound is known to activate heat shock proteins, which can indirectly protect and stabilize Lamin B1 during cellular stress conditions.

Pravastatin

81093-37-0sc-222188
50 mg
$408.00
1
(1)

Similar to lovastatin, pravastatin is a statin drug. It can activate Lamin B1 by affecting the mevalonate pathway and modulating the prenylation of Lamin B1.

Zoledronic acid, anhydrous

118072-93-8sc-364663
sc-364663A
25 mg
100 mg
$92.00
$256.00
5
(0)

Zoledronic acid can activate Lamin B1 through its role in bone health. It indirectly supports Lamin B1 function by regulating bone metabolism, as Lamin B1 is essential for maintaining the nuclear envelope in bone cells.