Lamin A/C Antibody (A-5): sc-398927
- Lamin A/C Antibody (A-5) is a mouse monoclonal IgG1 κ, cited in 7 publications, provided at 200 µg/ml
- raised against amino acids 231-340 mapping within an internal region of Lamin A of human origin
- recommended for detection of Lamin A/C of mouse, rat and human origin by WB, IP, IF and ELISA
- See Lamin A/C (E-1): sc-376248 for Lamin A/C antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Lamin A/C Antibody (A-5) for WB applications. These reagents are now offered in bundles with Lamin A/C Antibody (A-5) (see ordering information below).
Lamin A/C Antibody (A-5) is a mouse monoclonal IgG1 antibody that detects Lamin A/C in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Lamin A/C plays a crucial role in maintaining the structural integrity of the nuclear envelope, which is essential for proper cellular function and longevity. Lamin A/C is located in the nuclear lamina, a dense fibrillar network inside the nucleus, where Lamin A/C provides mechanical support and regulates important processes such as DNA replication and cell division. Disruptions in Lamin A/C expression or structure can lead to various diseases, including muscular dystrophies and progeria, a premature aging disorder. Lamin A undergoes post-translational modifications, including phosphorylation and farnesylation, which can influence interactions with other nuclear proteins and affect cellular signaling pathways. Anti-Lamin A/C antibody (A-5) serves as an invaluable tool for researchers studying nuclear envelope dynamics and implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lamin A/C Antibody (A-5) | sc-398927 | 200 µg/ml | $322.00 | |||
Lamin A/C Antibody (A-5): m-IgG Fc BP-HRP Bundle | sc-538546 | 200 µg Ab; 10 µg BP | $361.00 | |||
Lamin A/C Antibody (A-5): m-IgGκ BP-HRP Bundle | sc-536181 | 200 µg Ab; 40 µg BP | $361.00 | |||
Lamin A/C Antibody (A-5): m-IgG1 BP-HRP Bundle | sc-545758 | 200 µg Ab; 20 µg BP | $361.00 |