Ku86 Antibody (B-4): sc-515736
- Ku86 Antibody (B-4) is a mouse monoclonal IgG1 κ, cited in 6 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 711-730 at the C-terminus of Ku86 of mouse origin
- Anti-Ku86 Antibody (B-4) is recommended for detection of Ku86 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-Ku86 Antibody (B-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Ku86 Antibody (B-4) for WB and IHC(P) applications. These reagents are now offered in bundles with Ku86 Antibody (B-4) (see ordering information below).
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Ku86 Antibody (B-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects Ku86 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). anti-Ku86 antibody (B-4) is available in both non-conjugated and multiple conjugated forms, such as agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates. Ku86, which is part of the Ku heterodimer alongside Ku70, plays a crucial role in the cellular response to DNA damage and is essential for the repair of double-strand breaks through non-homologous end joining. This function is vital for maintaining genomic stability, as failure to repair DNA damage can lead to mutations, cancer, and other diseases. Ku86 is predominantly localized in the nucleus, where Ku86 binds to DNA and interacts with various proteins involved in DNA repair and transcription regulation. The presence of Ku86 in the nucleus underscores its importance in cellular processes that safeguard the integrity of the genome, making Ku86 a significant target for research in cancer biology and therapeutic development.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ku86 Antibody (B-4) | sc-515736 | 200 µg/ml | $316.00 | |||
Ku86 Antibody (B-4): m-IgG Fc BP-HRP Bundle | sc-531490 | 200 µg Ab; 10 µg BP | $354.00 | |||
Ku86 Antibody (B-4): m-IgGκ BP-HRP Bundle | sc-525189 | 200 µg Ab, 40 µg BP | $354.00 | |||
Ku86 Antibody (B-4): m-IgG1 BP-HRP Bundle | sc-544588 | 200 µg Ab; 20 µg BP | $354.00 | |||
Ku86 Antibody (B-4) AC | sc-515736 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Ku86 Antibody (B-4) HRP | sc-515736 HRP | 200 µg/ml | $316.00 | |||
Ku86 Antibody (B-4) FITC | sc-515736 FITC | 200 µg/ml | $330.00 | |||
Ku86 Antibody (B-4) PE | sc-515736 PE | 200 µg/ml | $343.00 | |||
Ku86 Antibody (B-4) Alexa Fluor® 488 | sc-515736 AF488 | 200 µg/ml | $357.00 | |||
Ku86 Antibody (B-4) Alexa Fluor® 546 | sc-515736 AF546 | 200 µg/ml | $357.00 | |||
Ku86 Antibody (B-4) Alexa Fluor® 594 | sc-515736 AF594 | 200 µg/ml | $357.00 | |||
Ku86 Antibody (B-4) Alexa Fluor® 647 | sc-515736 AF647 | 200 µg/ml | $357.00 | |||
Ku86 Antibody (B-4) Alexa Fluor® 680 | sc-515736 AF680 | 200 µg/ml | $357.00 | |||
Ku86 Antibody (B-4) Alexa Fluor® 790 | sc-515736 AF790 | 200 µg/ml | $357.00 |