KLF17 Antibody (B-6): sc-398132
- KLF17 Antibody (B-6) is a mouse monoclonal IgG2b κ KLF17 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 178-199 within an internal region of KLF17 of human origin
- KLF17 Antibody (B-6) is recommended for detection of KLF17 of human origin by WB, IP, IF and ELISA
- Anti-KLF17 Antibody (B-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for KLF17 Antibody (B-6) for WB applications. These reagents are now offered in bundles with KLF17 Antibody (B-6) (see ordering information below).
KLF17 Antibody (B-6) is a mouse monoclonal IgG2b kappa light chain antibody that detects KLF17 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-KLF17 antibody (B-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. KLF17, also known as zinc finger protein 393 or ZNF393, is a 389 amino acid nuclear protein that plays a crucial role in germ cell development, particularly in oocyte maturation and spermatid differentiation. KLF17 is primarily expressed in the testis and ovary, where KLF17 functions as a transcription factor that binds to G/C-rich sites through three C2H2-type zinc fingers, thereby activating transcription from CACCC-box elements. KLF17 regulation of gene expression is vital for proper reproductive development, and dysregulation may contribute to fertility issues. Using KLF17 (B-6) monoclonal antibody in research can provide insights into molecular mechanisms underlying germ cell differentiation and broader implications for reproductive health.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
KLF17 Antibody (B-6) References:
- Sp1 and krüppel-like factor family of transcription factors in cell growth regulation and cancer. | Black, AR., et al. 2001. J Cell Physiol. 188: 143-60. PMID: 11424081
- Identification of Zfp393, a germ cell-specific gene encoding a novel zinc finger protein. | Yan, W., et al. 2002. Mech Dev. 118: 233-9. PMID: 12351194
- Sp1- and Krüppel-like transcription factors. | Kaczynski, J., et al. 2003. Genome Biol. 4: 206. PMID: 12620113
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. | Kimura, K., et al. 2006. Genome Res. 16: 55-65. PMID: 16344560
- Human KLF17 is a new member of the Sp/KLF family of transcription factors. | van Vliet, J., et al. 2006. Genomics. 87: 474-82. PMID: 16460907
- KLF17 is a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. | Gumireddy, K., et al. 2009. Nat Cell Biol. 11: 1297-304. PMID: 19801974
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KLF17 Antibody (B-6) | sc-398132 | 200 µg/ml | $322.00 | |||
KLF17 Antibody (B-6): m-IgG Fc BP-HRP Bundle | sc-530698 | 200 µg Ab; 10 µg BP | $361.00 | |||
KLF17 Antibody (B-6): m-IgGκ BP-HRP Bundle | sc-524225 | 200 µg Ab, 40 µg BP | $361.00 | |||
KLF17 Antibody (B-6) AC | sc-398132 AC | 500 µg/ml, 25% agarose | $424.00 | |||
KLF17 Antibody (B-6) HRP | sc-398132 HRP | 200 µg/ml | $322.00 | |||
KLF17 Antibody (B-6) FITC | sc-398132 FITC | 200 µg/ml | $336.00 | |||
KLF17 Antibody (B-6) PE | sc-398132 PE | 200 µg/ml | $349.00 | |||
KLF17 Antibody (B-6) Alexa Fluor® 488 | sc-398132 AF488 | 200 µg/ml | $364.00 | |||
KLF17 Antibody (B-6) Alexa Fluor® 546 | sc-398132 AF546 | 200 µg/ml | $364.00 | |||
KLF17 Antibody (B-6) Alexa Fluor® 594 | sc-398132 AF594 | 200 µg/ml | $364.00 | |||
KLF17 Antibody (B-6) Alexa Fluor® 647 | sc-398132 AF647 | 200 µg/ml | $364.00 | |||
KLF17 Antibody (B-6) Alexa Fluor® 680 | sc-398132 AF680 | 200 µg/ml | $364.00 | |||
KLF17 Antibody (B-6) Alexa Fluor® 790 | sc-398132 AF790 | 200 µg/ml | $364.00 | |||
KLF17 (B-6) Neutralizing Peptide | sc-398132 P | 100 µg/0.5 ml | $69.00 |