KAT II Antibody (B-4): sc-365847

KAT II Antibody (B-4) is a mouse monoclonal IgG1 antibody that detects KAT II in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). KAT II, a member of the class-I pyridoxal-phosphate-dependent aminotransferase family, plays a crucial role in lysine degradation, which is essential for maintaining amino acid homeostasis and energy metabolism within cells. This mitochondrial protein is predominantly expressed in the liver, but is also found in significant amounts in the heart, brain, kidney, pancreas, ovary, and testis, highlighting KAT II′s importance in various physiological processes across different tissues. KAT II functions by catalyzing the conversion of L-2-aminoadipate and 2-oxoglutarate into 2-oxoglutaramate and L-glutamate, and operates as a homodimer, which is vital for enzymatic activity and stability. KAT II (B-4) antibody provides a reliable tool for researchers investigating KAT II′s role in metabolic pathways and implications in health and disease.

The preferred KAT II antibody is KAT II Antibody (G-4): sc-377158.