JunB Antibody (C-11): sc-8051
- JunB Antibody (C-11) is a mouse monoclonal IgG1 κ JunB antibody, cited in 160 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 210-222 near the C-terminus of Jun B of mouse origin
- JunB Antibody (C-11) is recommended for detection of Jun B of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-JunB Antibody (C-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to TRITC for IF, IHC(P) and FCM
- TransCruz reagent for Gel Supershift and ChIP applications (sc-8051 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for JunB Antibody (C-11) for WB and IHC(P) applications. These reagents are now offered in bundles with JunB Antibody (C-11) (see ordering information below).
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Jun B Antibody (C-11) is a mouse monoclonal IgG1 kappa light chain antibody that detects Jun B of mouse, rat, and human origin through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry (IHC), and enzyme-linked immunosorbent assay (ELISA). Jun B (C-11) antibody is offered in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase, phycoerythrin, fluorescein isothiocyanate, and multiple Alexa Fluor® conjugates. Jun B plays a crucial role in regulating gene expression and is a key component of the AP-1 transcriptional complex, which is essential for various cellular processes, including proliferation, differentiation, and apoptosis. Jun B can form homodimers or heterodimers with c-Fos and other members of the Fos gene family, allowing binding to specific DNA sequences and modulation of target gene transcription. Jun B interaction with these proteins and regulation of transcription is vital for cellular responses to growth factors and stress signals, making Jun B an important player in oncogenic processes and cellular signaling pathways.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
JunB Antibody (C-11) References:
- N-RAS and K-RAS gene mutations in Brazilian patients with multiple myeloma. | Ortega, MM., et al. 2006. Leuk Lymphoma. 47: 285-9. PMID: 16321859
- Overexpression of c-jun, junB, or junD affects cell growth differently. | Castellazzi, M., et al. 1991. Proc Natl Acad Sci U S A. 88: 8890-4. PMID: 1924349
- jun: oncogene and transcription factor. | Vogt, PK. and Bos, TJ. 1990. Adv Cancer Res. 55: 1-35. PMID: 2166997
- The small GTPase N-Ras regulates extracellular matrix synthesis, proliferation and migration in fibroblasts. | Fuentes-Calvo, I., et al. 2013. Biochim Biophys Acta. 1833: 2734-2744. PMID: 23871832
- jun-D: a third member of the jun gene family. | Ryder, K., et al. 1989. Proc Natl Acad Sci U S A. 86: 1500-3. PMID: 2493644
- The product of a fos-related gene, fra-1, binds cooperatively to the AP-1 site with Jun: transcription factor AP-1 is comprised of multiple protein complexes. | Cohen, DR., et al. 1989. Genes Dev. 3: 173-84. PMID: 2497053
- Characterization of junD: a new member of the jun proto-oncogene family. | Hirai, SI., et al. 1989. EMBO J. 8: 1433-9. PMID: 2504580
- The avian cellular homolog of the oncogene jun. | Nishimura, T. and Vogt, PK. 1988. Oncogene. 3: 659-63. PMID: 2577867
- Avian sarcoma virus 17 carries the jun oncogene. | Maki, Y., et al. 1987. Proc Natl Acad Sci U S A. 84: 2848-52. PMID: 3033666
- Fos and Jun: the AP-1 connection. | Curran, T. and Franza, BR. 1988. Cell. 55: 395-7. PMID: 3141060
- Induction of protooncogene c-jun by serum growth factors. | Ryder, K. and Nathans, D. 1988. Proc Natl Acad Sci U S A. 85: 8464-7. PMID: 3186736
- N-ras mutation of thyroid tumor with special reference to the follicular type. | Oyama, T., et al. 1995. Pathol Int. 45: 45-50. PMID: 7704243
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
JunB Antibody (C-11) | sc-8051 | 200 µg/ml | $322.00 | |||
JunB Antibody (C-11): m-IgG Fc BP-HRP Bundle | sc-528216 | 200 µg Ab; 10 µg BP | $361.00 | |||
JunB Antibody (C-11): m-IgGκ BP-HRP Bundle | sc-520539 | 200 µg Ab, 40 µg BP | $361.00 | |||
JunB Antibody (C-11): m-IgG1 BP-HRP Bundle | sc-542821 | 200 µg Ab; 20 µg BP | $361.00 | |||
JunB Antibody (C-11) X | sc-8051 X | 200 µg/0.1 ml | $322.00 | |||
JunB Antibody (C-11) AC | sc-8051 AC | 500 µg/ml, 25% agarose | $424.00 | |||
JunB Antibody (C-11) HRP | sc-8051 HRP | 200 µg/ml | $322.00 | |||
JunB Antibody (C-11) FITC | sc-8051 FITC | 200 µg/ml | $336.00 | |||
JunB Antibody (C-11) PE | sc-8051 PE | 200 µg/ml | $349.00 | |||
JunB Antibody (C-11) Alexa Fluor® 488 | sc-8051 AF488 | 200 µg/ml | $364.00 | |||
JunB Antibody (C-11) Alexa Fluor® 546 | sc-8051 AF546 | 200 µg/ml | $364.00 | |||
JunB Antibody (C-11) Alexa Fluor® 594 | sc-8051 AF594 | 200 µg/ml | $364.00 | |||
JunB Antibody (C-11) Alexa Fluor® 647 | sc-8051 AF647 | 200 µg/ml | $364.00 | |||
JunB Antibody (C-11) Alexa Fluor® 680 | sc-8051 AF680 | 200 µg/ml | $364.00 | |||
JunB Antibody (C-11) Alexa Fluor® 790 | sc-8051 AF790 | 200 µg/ml | $364.00 | |||
JunB Antibody (C-11) TRITC | sc-8051 TRITC | 200 µg/ml | $326.00 | |||
JunB (C-11) Neutralizing Peptide | sc-8051 P | 100 µg/0.5 ml | $69.00 |