ISYNA1 Antibody (C-8): sc-377245
- ISYNA1 Antibody (C-8) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 219-253 within an internal region of ISYNA1 of human origin
- recommended for detection of ISYNA1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and canine and bovine
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ISYNA1 Antibody (C-8) for WB and IHC(P) applications. These reagents are now offered in bundles with ISYNA1 Antibody (C-8) (see ordering information below).
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ISYNA1 Antibody (C-8) is a mouse monoclonal IgG2b antibody that detects ISYNA1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). ISYNA1, also known as inositol-3-phosphate synthase 1, plays a crucial role in the biosynthesis of myo-inositol, a vital component of membrane phospholipids and a precursor for the phosphoinositide signaling pathway. This 558 amino acid enzyme is predominantly expressed in the testis, ovary, heart, placenta, and pancreas, with lower levels found in blood leukocytes, thymus, skeletal muscle, and colon. The significance of ISYNA1 lies in its function as the rate-limiting enzyme in the synthesis of all inositol-containing compounds, catalyzing the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner. The regulation of ISYNA1 is also noteworthy, as ISYNA1 can be upregulated by E2F-1 and inhibited by mood-stabilizing drugs such as valproate and lithium, highlighting potential implications in metabolic and psychiatric disorders. With proven detection capabilities, anti-ISYNA1 antibody (C-8) serves as an essential tool for researchers investigating cellular signaling and metabolic processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ISYNA1 Antibody (C-8) | sc-377245 | 200 µg/ml | $322.00 | |||
ISYNA1 Antibody (C-8): m-IgG Fc BP-HRP Bundle | sc-538028 | 200 µg Ab; 10 µg BP | $361.00 | |||
ISYNA1 Antibody (C-8): m-IgGκ BP-HRP Bundle | sc-535549 | 200 µg Ab; 40 µg BP | $361.00 | |||
ISYNA1 (C-8) Neutralizing Peptide | sc-377245 P | 100 µg/0.5 ml | $69.00 |