ISYNA1 Activators
ISYNA1 activators refer to a class of chemicals that enhance the activity of inositol-3-phosphate synthase 1 (ISYNA1), an enzyme responsible for the synthesis of myo-inositol-3-phosphate from glucose-6-phosphate. This reaction is a key initial step in the inositol biosynthesis pathway, which is critical for the production of inositol and inositol-containing compounds. These compounds play pivotal roles in a variety of cellular processes, including signal transduction, osmoregulation, and membrane trafficking.
Direct activators of ISYNA1 may interact with the enzyme at the active site, stabilizing the transition state of the reaction or altering the enzyme conformation in a way that increases its affinity for the substrate or its catalytic turnover rate. Such activators could also mimic the substrate or intermediate states of the enzymatic reaction, thus enhancing the enzyme's activity by facilitating the proper orientation or by reducing the activation energy required for the reaction to proceed. Indirect activators could increase ISYNA1 activity by upregulating the expression of the ISYNA1 gene, thereby increasing enzyme levels within the cell. Alternatively, they may inhibit the degradation pathways of ISYNA1, leading to a prolonged half-life and greater enzymatic activity over time. Indirect activators might also function by affecting the availability of the substrate or the cellular conditions, such as pH and ionic strength, which are conducive to optimal enzyme activity.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium Chloride inhibits inositol monophosphatase, leading to increased levels of inositol phosphates. This inhibition can enhance the activity of ISYNA1 by upregulating the synthesis of inositol to replenish the depleted pools. | ||||||
Calcium chloride anhydrous | 10043-52-4 | sc-207392 sc-207392A | 100 g 500 g | $66.00 $262.00 | 1 | |
Calcium Chloride can increase intracellular calcium levels, which may activate calcium/calmodulin-dependent kinase (CaMK), subsequently enhancing the activity of ISYNA1 by promoting inositol synthesis as part of a signaling cascade. | ||||||
Magnesium sulfate anhydrous | 7487-88-9 | sc-211764 sc-211764A sc-211764B sc-211764C sc-211764D | 500 g 1 kg 2.5 kg 5 kg 10 kg | $46.00 $69.00 $163.00 $245.00 $418.00 | 3 | |
Magnesium is a cofactor for many enzymes, including those involved in phosphorylation pathways. Magnesium Sulfate supplementation can enhance the enzymatic activity of ISYNA1 by ensuring optimal cofactor availability. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $57.00 $191.00 $302.00 $450.00 $1800.00 $3570.00 $10710.00 | 4 | |
NAD+ is a substrate for ADP-ribosylation factors, which can influence membrane trafficking. Increased NAD+ levels can indirectly enhance ISYNA1 activity by optimizing membrane-associated processes essential for its function. | ||||||
L-α-Lecithin, Egg Yolk, Highly Purified | 8002-43-5 | sc-203096 | 250 mg | $135.00 | ||
L-α-Lecithin can modulate membrane fluidity and curvature, potentially enhancing the activity of membrane-associated enzymes like ISYNA1 by providing an optimal lipid environment for its function. | ||||||
D(−)Mannitol | 69-65-8 | sc-203020A sc-203020 | 50 g 100 g | $10.00 $19.00 | 2 | |
Mannitol is an osmotic agent that can affect cellular water balance, indirectly influencing the activity of enzymes like ISYNA1 by modifying the intracellular environment and potentially enhancing its catalytic efficiency. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc acts as a cofactor for many enzymes and can influence phosphorylation signaling pathways. Zinc Sulfate may enhance ISYNA1 activity by acting as a cofactor, directly participating in the catalytic reaction of the enzyme. | ||||||
FCM Lysing solution (1x) | sc-3621 | 150 ml | $62.00 | 8 | ||
Ammonium Chloride can affect intracellular pH, which may alter enzyme activities. The activity of ISYNA1 could be indirectly enhanced by optimizing the pH environment for its catalytic activity. | ||||||
Choline chloride | 67-48-1 | sc-207430 sc-207430A sc-207430B | 10 mg 5 g 50 g | $33.00 $37.00 $52.00 | 1 | |
Choline Chloride can indirectly enhance ISYNA1 activity by serving as a precursor for the synthesis of phosphatidylcholine, a major component of membranes where ISYNA1 may be active. | ||||||
Ethanolamine | 141-43-5 | sc-203042 sc-203042A sc-203042B | 25 ml 500 ml 2.5 L | $22.00 $56.00 $204.00 | 1 | |
Ethanolamine serves as a precursor for phospholipid synthesis, potentially enhancing the activity of ISYNA1 by supporting membrane synthesis and turnover, thereby indirectly influencing ISYNA1's function in the cell. | ||||||