IRF-7 Antibody (F-1): sc-74471
- IRF-7 Antibody (F-1) is a mouse monoclonal IgG2a κ, cited in 22 publications, provided at 200 µg/ml
- raised against amino acids 1-246 of IRF-7 of human origin
- Anti-IRF-7 Antibody (F-1) is recommended for detection of IRF-7 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-IRF-7 Antibody (F-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for Gel Supershift and ChIP applications (sc-74471 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for IRF-7 Antibody (F-1) for WB applications. These reagents are now offered in bundles with IRF-7 Antibody (F-1) (see ordering information below).
IRF-7 Antibody (F-1) is a mouse monoclonal IgG2a kappa light chain antibody that detects IRF-7 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-IRF-7 antibody (F-1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Interferon regulatory factor 7 (IRF-7) plays a crucial role in immune response by regulating type I interferons, which are vital for antiviral defense. Located primarily in the nucleus, IRF-7 becomes activated in response to viral infections and is essential for transcriptional activation of interferon-α and interferon-β genes. This nuclear localization enables IRF-7 to quickly respond to viral signals and initiate immune response, enhancing host′s ability to combat infections. IRF-7 interacts with other proteins in interferon signaling pathway, including IRF-3, which further underscores IRF-7′s importance in regulating immune responses. Formation of protein complexes by IRF-7 highlights a critical role in fine-tuning immune response, making IRF-7 an important target for research in immunology and virology.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IRF-7 Antibody (F-1) | sc-74471 | 200 µg/ml | $316.00 | |||
IRF-7 Antibody (F-1): m-IgG Fc BP-HRP Bundle | sc-525718 | 200 µg Ab; 10 µg BP | $354.00 | |||
IRF-7 Antibody (F-1): m-IgG2a BP-HRP Bundle | sc-546378 | 200 µg Ab; 10 µg BP | $354.00 | |||
IRF-7 Antibody (F-1) X | sc-74471 X | 200 µg/0.1 ml | $316.00 | |||
IRF-7 Antibody (F-1) AC | sc-74471 AC | 500 µg/ml, 25% agarose | $416.00 | |||
IRF-7 Antibody (F-1) HRP | sc-74471 HRP | 200 µg/ml | $316.00 | |||
IRF-7 Antibody (F-1) FITC | sc-74471 FITC | 200 µg/ml | $330.00 | |||
IRF-7 Antibody (F-1) PE | sc-74471 PE | 200 µg/ml | $343.00 | |||
IRF-7 Antibody (F-1) Alexa Fluor® 488 | sc-74471 AF488 | 200 µg/ml | $357.00 | |||
IRF-7 Antibody (F-1) Alexa Fluor® 546 | sc-74471 AF546 | 200 µg/ml | $357.00 | |||
IRF-7 Antibody (F-1) Alexa Fluor® 594 | sc-74471 AF594 | 200 µg/ml | $357.00 | |||
IRF-7 Antibody (F-1) Alexa Fluor® 647 | sc-74471 AF647 | 200 µg/ml | $357.00 | |||
IRF-7 Antibody (F-1) Alexa Fluor® 680 | sc-74471 AF680 | 200 µg/ml | $357.00 | |||
IRF-7 Antibody (F-1) Alexa Fluor® 790 | sc-74471 AF790 | 200 µg/ml | $357.00 |