Integrin αIIb/ITGA2B/CD41 Antibody (B-10): sc-166599
- Integrin αIIb/ITGA2B/CD41 Antibody (B-10) is a mouse monoclonal IgG2b, cited in 6 publications, provided at 200 µg/ml
- raised against amino acids 847-1006 mapping near the C-terminus of Integrin αIIb of human origin
- recommended for detection of Integrin αIIb heavy and light chain of human origin by WB, IP, IF and ELISA
- See Integrin αIIb/ITGA2B/CD41 (B-9): sc-365938 for Integrin αIIb/ITGA2B/CD41 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Integrin αIIb/ITGA2B/CD41 Antibody (B-10). This work is in progress.
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SEE ALSO...
Integrin αIIb Antibody (B-10) is a mouse monoclonal IgG2b antibody that detects Integrin αIIb in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Integrin αIIb is a crucial component of the integrin family, primarily expressed on platelets, where anti-Integrin αIIb antibody (B-10) plays a vital role in hemostasis and thrombosis by mediating platelet aggregation. This protein forms a heterodimer with the β3 subunit, resulting in the integrin αIIbβ3 complex, which is essential for binding to fibrinogen and other extracellular matrix proteins. The ability of Integrin αIIb to interact with these ligands is critical for the formation of stable platelet aggregates, which is necessary for proper blood clotting and wound healing. Dysregulation of Integrin αIIb function can lead to various bleeding disorders, highlighting its importance in maintaining vascular integrity. Integrin αIIb monoclonal antibody (B-10) is an invaluable tool for researchers studying platelet biology, cardiovascular diseases, and the mechanisms of thrombosis, providing insights into the therapeutic targeting of integrin pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Integrin αIIb/ITGA2B/CD41 Antibody (B-10) | sc-166599 | 200 µg/ml | $316.00 |