Integrin α5/ITGA5/CD49e Antibody (B-4): sc-166681

Integrin α5 Antibody (B-4) is a mouse monoclonal IgG1 antibody that detects Integrin α5 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Integrin α5 plays a crucial role in cell adhesion and signaling, primarily by forming heterodimers with the β1 subunit to create the α5β1 integrin receptor, which is essential for binding to extracellular matrix components such as fibronectin. This interaction is vital for numerous biological processes, including cell migration, proliferation, and differentiation, making anti-Integrin α5 antibody (B-4) a key tool for studying tissue development and repair. Integrin α5′s ability to mediate cell adhesion not only facilitates the structural integrity of tissues but also influences cellular responses to external stimuli, thereby impacting processes such as wound healing and immune responses. Furthermore, the dynamic regulation of Integrin α5 expression and its interactions with other signaling molecules underscore its importance in maintaining cellular homeostasis and responding to pathological conditions. Integrin α5 monoclonal antibody (B-4) serves as an invaluable tool for researchers investigating the intricate roles of integrins in health and disease.

The preferred Integrin α5/ITGA5/CD49e antibody is Integrin α5/ITGA5/CD49e Antibody (P1D6): sc-13547.