IL-6Rα Antibody (H-7): sc-373708
- IL-6Rα Antibody (H-7) is a mouse monoclonal IgG1 κ, cited in 28 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 441-468 at the C-terminus of IL-6Rα of human origin
- Anti-IL-6R alpha Antibody (H-7) is recommended for detection of IL-6Rα of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-IL-6R alpha Antibody (H-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for IL-6Rα Antibody (H-7) for WB and IHC(P) applications. This reagent is now offered in a bundle with IL-6Rα Antibody (H-7) (see ordering information below).
QUICK LINKS
IL-6Rα Antibody (H-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects IL-6Rα in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). IL-6Rα (H-7) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. IL-6Rα serves as a receptor for interleukin-6 (IL-6), a cytokine involved in inflammation and immune response. Upon binding of IL-6 to IL-6Rα, the receptor forms a complex with gp130, leading to activation of intracellular signaling pathways that regulate cell proliferation, differentiation, and survival. This signaling is particularly important in inflammatory diseases and certain cancers, where dysregulation of IL-6 signaling can contribute to disease progression. Additionally, the soluble form of IL-6Rα, generated through proteolytic cleavage, can enhance IL-6 activity, further emphasizing IL-6Rα′s significance in mediating immune responses and potential as a therapeutic target.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IL-6Rα Antibody (H-7) | sc-373708 | 200 µg/ml | $316.00 | |||
IL-6Rα Antibody (H-7): m-IgG Fc BP-HRP Bundle | sc-525917 | 200 µg Ab; 10 µg BP | $354.00 | |||
IL-6Rα Antibody (H-7) AC | sc-373708 AC | 500 µg/ml, 25% agarose | $416.00 | |||
IL-6Rα Antibody (H-7) HRP | sc-373708 HRP | 200 µg/ml | $316.00 | |||
IL-6Rα Antibody (H-7) FITC | sc-373708 FITC | 200 µg/ml | $330.00 | |||
IL-6Rα Antibody (H-7) PE | sc-373708 PE | 200 µg/ml | $343.00 | |||
IL-6Rα Antibody (H-7) Alexa Fluor® 488 | sc-373708 AF488 | 200 µg/ml | $357.00 | |||
IL-6Rα Antibody (H-7) Alexa Fluor® 546 | sc-373708 AF546 | 200 µg/ml | $357.00 | |||
IL-6Rα Antibody (H-7) Alexa Fluor® 594 | sc-373708 AF594 | 200 µg/ml | $357.00 | |||
IL-6Rα Antibody (H-7) Alexa Fluor® 647 | sc-373708 AF647 | 200 µg/ml | $357.00 | |||
IL-6Rα Antibody (H-7) Alexa Fluor® 680 | sc-373708 AF680 | 200 µg/ml | $357.00 | |||
IL-6Rα Antibody (H-7) Alexa Fluor® 790 | sc-373708 AF790 | 200 µg/ml | $357.00 | |||
IL-6Rα (H-7) Neutralizing Peptide | sc-373708 P | 100 µg/0.5 ml | $68.00 |