Date published: 2026-5-14

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IL-6R α Antibodies

Santa Cruz Biotechnology features a diverse variety of IL-6R α monoclonal antibodies for research focused on understanding interleukin-6 receptor alpha in various biological processes. IL-6R α monoclonal antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Interleukin-6 receptor alpha (IL-6R α) is a critical component of the IL-6 signaling pathway, which plays a significant role in immune response, inflammation, and hematopoiesis. Dysregulation of IL-6R α has been implicated in various diseases, including autoimmune disorders and cancers, making it an important target for therapeutic intervention. Understanding the function of IL-6R α can provide insights into disease mechanisms and potential treatment strategies. IL-6R α monoclonal antibodies enable precise detection and analysis of protein expression patterns across different experimental conditions. Researchers can utilize IL-6R α monoclonal antibodies to investigate cellular localization and protein-protein interactions. IL-6R α monoclonal antibodies support detailed pathway analysis and protein characterization studies. Santa Cruz Biotechnology monoclonal antibodies for IL-6R α contribute to advancing scientific understanding of immune system regulation and disease mechanisms.

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IL-6R α Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

IL-6Rα Antibody (D-8)

sc-374259mouse IgG1 κ433-460 (m)WB, IP, IF, ELISAm, r
14
(5)

IL-6Rα Antibody (H-7)

sc-373708mouse IgG1 κ441-468 (h)WB, IP, IF, IHC(P), ELISAm, r, h
28
(8)

IL-6Rα Antibody (2B2.3)

sc-71366mouse IgG1(h)FCM
1
(1)

IL-6R α CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-6Rα CRISPR/Cas9 KO Plasmid (h2)

sc-400582-KO-2hGene KnockoutGFP0
(0)

IL-6Rα HDR Plasmid (h2)

sc-400582-HDR-2hHomology Directed RepairPuromycin0
(0)

IL-6Rα Double Nickase Plasmid (h)

sc-400582-NIChGene KnockoutPuromycin0
(0)

IL-6Rα Double Nickase Plasmid (h2)

sc-400582-NIC-2hGene KnockoutPuromycin0
(0)

IL-6Rα CRISPR/Cas9 KO Plasmid (m)

sc-421115mGene KnockoutGFP0
(0)

IL-6Rα HDR Plasmid (m)

sc-421115-HDRmHomology Directed RepairPuromycin0
(0)

IL-6R α CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-6Rα CRISPR Activation Plasmid (h)

sc-400582-ACThGene ActivationPuro, Blast, Hygro0
(0)

IL-6Rα CRISPR Activation Plasmid (h2)

sc-400582-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

IL-6R α siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-6Rα siRNA (h)

sc-35663hGene SilencingN/A
5
(0)

IL-6Rα shRNA Plasmid (h)

sc-35663-SHhGene SilencingPuromycin
5
(0)

IL-6Rα shRNA (h) Lentiviral Particles

sc-35663-VhGene SilencingPuromycin
5
(0)

IL-6Rα siRNA (m)

sc-40065mGene SilencingN/A
2
(0)

IL-6Rα shRNA Plasmid (m)

sc-40065-SHmGene SilencingPuromycin
2
(0)

IL-6Rα shRNA (m) Lentiviral Particles

sc-40065-VmGene SilencingPuromycin
2
(0)