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IL-3Rα Antibody (6H6) is a mouse monoclonal IgG1 antibody that detects IL-3Rα in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). IL-3Rα, or interleukin-3 receptor alpha, plays a crucial role in the immune system by serving as the specific binding site for interleukin-3, a cytokine that promotes the growth and differentiation of hematopoietic cells. IL-3Rα is primarily located on the surface of hematopoietic progenitor cells, where IL-3Rα facilitates the activation of downstream signaling pathways essential for cell survival and proliferation. The interaction between IL-3 and IL-3Rα is vital for the maintenance of normal blood cell production and immune responses, making IL-3Rα a significant target for therapeutic interventions in conditions such as leukemia and other hematological disorders. Notably, the IL-3 receptor complex also includes the common β subunit, which is shared with the receptors for IL-5 and GM-CSF, highlighting the interconnectedness of these signaling pathways in regulating hematopoiesis. Anti-IL-3Rα antibody (6H6) is an invaluable tool for researchers studying the dynamics of immune cell development and function, as well as the molecular mechanisms underlying various hematological diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IL-3Rα Antibody (6H6) | sc-80650 | 200 µg/ml | $316.00 | |||
IL-3Rα Antibody (6H6): m-IgG Fc BP-HRP Bundle | sc-537236 | 200 µg Ab; 10 µg BP | $354.00 | |||
IL-3Rα Antibody (6H6): m-IgGκ BP-HRP Bundle | sc-534456 | 200 µg Ab; 40 µg BP | $354.00 | |||
IL-3Rα Antibody (6H6): m-IgG1 BP-HRP Bundle | sc-545095 | 200 µg Ab; 20 µg BP | $354.00 |