IL-2Rγ Antibody (G-3): sc-374179

IL-2Rγ Antibody (G-3) is a mouse monoclonal IgG1 antibody that detects IL-2Rγ in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). IL-2Rγ, also known as the common gamma chain (γc), plays a crucial role in the immune system by serving as a shared subunit for several interleukin receptors, including IL-2, IL-4, IL-7, and IL-13. IL-2Rγ is primarily located on the surface of immune cells, such as T cells, where IL-2Rγ facilitates high-affinity binding of interleukins, thereby triggering essential signaling pathways that promote T cell proliferation and differentiation. IL-2Rγ is vital for the proper functioning of these cytokine receptors, as IL-2Rγ enhances ligand binding and ensures effective immune responses. Importantly, mutations or deficiencies in IL-2Rγ can lead to severe combined immunodeficiency (SCID), highlighting IL-2Rγ′s significance in maintaining immune system integrity. Anti-IL-2Rγ antibody (G-3) is an invaluable tool for researchers studying immune responses, cytokine signaling, and related pathologies.

The preferred IL-2Rγ antibody is IL-2Rγ Antibody (A-10): sc-271060.