IL-2Rγ Antibody (E-7): sc-365910

IL-2Rγ Antibody (E-7) is a mouse monoclonal IgG1 antibody that detects IL-2Rγ in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). IL-2Rγ, also known as the common gamma chain (γc), plays a crucial role in the immune system by serving as a shared subunit for several interleukin receptors, including IL-2, IL-4, IL-7, and IL-13. IL-2Rγ is primarily located on the surface of immune cells, such as T cells, where IL-2Rγ is essential for high-affinity binding of interleukins, which in turn triggers signaling pathways that promote T cell proliferation and differentiation. IL-2Rγ is vital for the proper functioning of these cytokine receptors, as IL-2Rγ enhances ligand binding and ensures effective immune responses. Mutations or deficiencies in the IL-2Rγ gene can lead to severe combined immunodeficiency (SCID), highlighting IL-2Rγ′s critical role in maintaining immune system integrity. With IL-2Rγ′s ability to facilitate the binding of multiple interleukins, anti-IL-2Rγ antibody (E-7) serves as an invaluable tool for researchers studying immune function and related disorders.

The preferred IL-2Rγ antibody is IL-2Rγ Antibody (A-10): sc-271060.